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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2006-6-29-34</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-1357</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТРАВМА. КРОВОПОТЕРЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INJURY. BLOOD LOSS</subject></subj-group></article-categories><title-group><article-title>Электрокардиографические нарушения при ушибе сердца (экспериментальное исследование)</article-title><trans-title-group xml:lang="en"><trans-title>Electrocardiographic Abnormalities in Cardiac Contusion: Experimental Study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корпачева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korpacheva</surname><given-names>O. V.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгих</surname><given-names>В. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgikh</surname><given-names>V. T.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Омская государственная медицинская академия, кафедра патофизиологии с курсом клинической патофизиологии</institution></aff><aff xml:lang="en"><institution>Department of Pathophysiology with a Course of Clinical Pathophysiology, Omsk State Medical Academy</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2006</year></pub-date><pub-date pub-type="epub"><day>20</day><month>12</month><year>2006</year></pub-date><volume>2</volume><issue>6</issue><issue-title>Том II № 5-6 2006 г.</issue-title><fpage>29</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корпачева О.В., Долгих В.Т., 2006</copyright-statement><copyright-year>2006</copyright-year><copyright-holder xml:lang="ru">Корпачева О.В., Долгих В.Т.</copyright-holder><copyright-holder xml:lang="en">Korpacheva O.V., Dolgikh V.T.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/1357">https://www.reanimatology.com/rmt/article/view/1357</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования : изучить частоту развития и структуру нарушений сердечного ритма и других ЭКГ-отклонений в раннем посттравматическом периоде экспериментального ушиба сердца, а также их вклад в летальность и формирование посттравматической миокардиальной дисфункции.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы: эксперименты выполнены на белых беспородных крысах-самцах, наркотизированных тиопенталом натрия. Регистрировали электрокардиограмму, частоту дыхания и АД в левой сонной артерии прямым методом. Ушиб сердца воспроизводили с помощью оригинального устройства, имитирующего удар передней грудной стенки о стойку руля при столкновении движущегося автомобиля с препятствием. У части животных травма наносилась после предварительного введения атропина сульфата.</p></sec><sec><title>Результаты</title><p>Результаты: обязательным и стойким ЭКГ-отклонением в раннем посттравматическом периоде изолированного экспериментального ушиба сердца является синусовая брадикардия, сопровождающаяся урежением или кратковременной остановкой дыхания и снижением артериального давления. Предварительное введение атропина в значительной степени предотвращает возникновение данных изменений и указывает на вероятный рефлекторный механизм их развития. Другие ЭКГ-отклонения (гетеротопные ритмы, экстрасистолия, блокады проведения, изменения конечной части желудочкового комплекса и др.) встречаются в самых разнообразных сочетаниях, в числе которых не удалось выявить типичных, носят разнообразный, кратковременный и лабильный характер. Среди них практически отсутствуют гемодинамически значимые и потенциально летальные нарушения ритма.</p></sec><sec><title>Заключение</title><p>Заключение: структура нарушений сердечного ритма при экспериментальном изолированном ушибе сердца отличается от таковой в условиях клиники. Нарушения сердечного ритма и другие ЭКГ-отклонения не вносят существенного вклада в показатель летальности в условиях данного эксперимента, поскольку среди них нет гемодинамически значимых.</p></sec><sec><title> </title><p> </p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective: to study the incidence and pattern of cardiac arrhythmias and other abnormalities in the early posttraumatic period of experimental cardiac contusion and to assess their contribution to death and the development of posttraumat-ic myocardial dysfunction.</p></sec><sec><title>Materials and methods</title><p>Materials and methods: experiments were carried out on non-inbred albino male rats anesthetized with sodium thiopental. An electrocardiogram, respiration rate, and left carotid blood pressure were recorded in the direct fashion. Cardiac contusion was reproduced by an original device that imitated a blow of the steering wheel to the anterior chest, as that observed when a moving car clashed against an obstacle. Some animals were traumatized after preadministration of atropine sulfate.</p></sec><sec><title>Results</title><p>Results: sinus bradycardia accompanied by bradypnoea or short-term apnoea and lowered blood pressure is a compulsory and persistent ECG abnormality. Preinjection of atropine significantly prevents the occurrence of these changes and points to the likely reflectory mechanism of their development. Other ECG abnormalities (heterotopic rhythms, premature beats, conduction blockade, terminal ventricular complex changes, etc.) are encountered in a variety of combinations, including those among which typical changes that are undetectable, are diverse, short-term, and labile. Among them, there are virtually no hemodynamic and potentially fatal arrhythmias.</p></sec><sec><title>Conclusion</title><p>Conclusion: in experimental isolated cardiac contusion, the pattern of cardiac arrhythmias differs from that observed in the inpatient setting. Cardiac arrhythmias and other ECG abnormalities do not make a considerable contribution to a mortality rate under the conditions of this experiment since there are no hemodynamic ones.</p></sec><sec><title> </title><p> </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>экспериментальный ушиб сердца</kwd><kwd>электрокардиографические нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>experimental cardiac contusion</kwd><kwd>electrocardiographic abnormalities</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сорокоумова Е. А., Мажара Ю. П. 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