rmtОбщая реаниматологияGeneral Reanimatology1813-97792411-7110FSBI "SRIGR" RAMS10.15360/1813-9779-2014-3-50-58rmt-1401Research ArticleПРАКТИКУЮЩЕМУ ВРАЧУFOR PRACTIONERВОЗМОЖНОСТИ ТЕРАПИИ ГЕМОРРАГИЧЕСКОГО ШОКА У БОЛЬНЫХ С ЖЕЛУДОЧНО-КИШЕЧНЫМ КРОВОТЕЧЕНИЕМPossibilities of Therapy for Hemorrhagic Shock in Patients with Gastrointestinal BleedingСимутисИ. С.SimutisI. S.simutis@mail.ruБояриновГ. А.BoyarinovG. A.МухинА. С.MukhinA. S.ПрилуковД. Б.PrilukovD. B.Городская клиническая больница N40, Нижний НовгородРоссияCity Clinical Hospital Forty, Nizhny NovgorodRussian FederationНижегородская Государственная Медицинская Академия, Нижний НовгородРоссияNizhny Novgorod State Medical Academy, Nizhny NovgorodRussian FederationПриволжский окружной медицинский центр ФМБА России, Нижний НовгородРоссияVolga District Medical Center, Federal Biomedical Agency of Russia, Nizhny NovgorodRussian Federation2014280620141035058Copyright © Симутис И., Бояринов Г., Мухин А., Прилуков Д., 20142014Симутис И., Бояринов Г., Мухин А., Прилуков Д.Simutis I., Boyarinov G., Mukhin A., Prilukov D.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.reanimatology.com/rmt/article/view/1401

Цель исследования — оценить противогипоксическое и антиоксидантное действие Мексикора у больных с желудочно-кишечными кровотечениями язвенной этиологии.

Материалы и методы

Материалы и методы. В статье представлены материалы, полученные в процессе лечения 53 больных язвенной болезнью с неварикозными желудочно-кишечными кровотечениями, госпитализированными в состоянии геморрагического шока II—III ст.

Результаты

Результаты. Установлено, что включение Мексикора в комплексную программу интенсивной терапии острых желудочно-кишечных кровотечений снижает в организме больных активность прооксидантных процессов, выраженность проявлений тканевой гипоксии и системного воспаления, улучшает показатели системной гемодинамики и клиническое течение раннего постгеморрагического периода.

Заключение

Заключение. Применение Мексикора у пациентов с желудочными кровотечениями снижает число осложнений, сокращает длительность лечения больных в отделении реанимации. 

Objective

Objective: to evaluate the antihypoxic effect of Mexicor in patients with gastrointestinal bleeding of ulcerative etiology.

Materials and methods

Materials and methods. The paper presents the materials obtained during the treatment of 53 patients with nonvaricose gastrointestinal bleeding who were hospitalized with grades II—III hemorrhagic shock.

Results

Results. Incorporation of Mexicor into the comprehensive program for the intensive therapy of acute gastrointestinal bleeding was ascertained to reduce the activity of prooxidant processes, and the manifestations of tissue hypoxia and systemic inflammation and to improve systemic hemodynamic parameters and the clinical course of an early posthemorrhagic period.

Conclusion

Conclusion. The use of Mexicor in patients with gastric bleeding reduces the number of complications and the duration of treatment in the intensive care unit.  

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The authors declare that there are no conflicts of interest present.