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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2014-4-51-73</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-1412</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS &amp; SHORT COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>ПРЕПАРАТЫ ЛЕГОЧНОГО СУРФАКТАНТА ПРИ ОСТРЫХ И ХРОНИЧЕСКИХ ЗАБОЛЕВАНИЯХ ЛЕГКИХ (Часть I)</article-title><trans-title-group xml:lang="en"><trans-title>Pulmonary Surfactants for Acute and Chronic Lung Diseases (Part I)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Розенберг</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Rozenberg</surname><given-names>O. A.</given-names></name></name-alternatives><email xlink:type="simple">rozenberg@biosurf.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский научный центр радиологии и хирургических технологий Минздрава России, Санкт-Петербург</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Research Center for Radiology and Surgical Technologies, Ministry of Health of the Russian Federation, Saint Petersburg</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2014</year></pub-date><volume>10</volume><issue>4</issue><fpage>51</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Розенберг О.А., 2014</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="ru">Розенберг О.А.</copyright-holder><copyright-holder xml:lang="en">Rozenberg O.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/1412">https://www.reanimatology.com/rmt/article/view/1412</self-uri><abstract><p>В первой части обзора приводятся сведения о составе и свойствах легочного сурфактанта, количественных и качественных нарушениях сурфактантной системы легких при различных патологических состояниях новорожденных и взрослых, описывается состав коммерческих синтетических и природных препаратов сурфактанта. Проводится анализ результатов сурфактанттерапии РДС и других заболеваний легких с вторичным дефицитом сурфактанта у новорожденных.</p></abstract><trans-abstract xml:lang="en"><p>Part 1 of the review gives information on the composition and properties of a pulmonary surfactant and quantitative and qual itative impairments in the pulmonary surfactant system in different neonatal and adult abnormalities and describes the composition of commercial synthetic and natural surfactants. The results of surfactant therapy for respiratory distress syndrome and other lung diseases with secondary surfactant deficiency in the newborns are analyzed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>легочный сурфактант</kwd><kwd>препараты сурфактанта</kwd><kwd>острые и хронические заболевания легких</kwd><kwd>РДС</kwd><kwd>ОРДС</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary surfactant</kwd><kwd>surfactants</kwd><kwd>acute and chronic lung diseases</kwd><kwd>respiratory distress syndrome</kwd><kwd>acute respiratory distress syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">King R.J., Clements J.A. Surface active materials from dog lung: composition and physiological correlations. Am. J. Physiol. 1972; 223 (3): 715—726. PMID: 506862</mixed-citation><mixed-citation xml:lang="en">King R.J., Clements J.A. 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