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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2017-3-35-47</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-1591</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТРАВМА И КРОВОПОТЕРЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INJURY, BLOOD LOSS</subject></subj-group></article-categories><title-group><article-title>Кислородный статус пострадавших с повреждениями органов брюшной полости во время операции</article-title><trans-title-group xml:lang="en"><trans-title>Intraoperative Oxygen Status in Patients with Injuries of Abdominal Cavity Organs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимербаев</surname><given-names>В. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Timerbaev</surname><given-names>Vladimir H.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129090, г. Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>3 Bolshaya Sukharevskaya pl., Moscow 129090</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Драгунов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dragunov</surname><given-names>Anton V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129090, г. Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>3 Bolshaya Sukharevskaya pl., Moscow 129090</p></bio><email xlink:type="simple">reanest@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Конохов</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Konokhov</surname><given-names>Pavel V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>129090, г. Москва, Большая Сухаревская пл., д. 3</p></bio><bio xml:lang="en"><p>3 Bolshaya Sukharevskaya pl., Moscow 129090</p></bio><email xlink:type="simple">konohov.pavlik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N. V. Sklifosovskiy Research Institute of Emergency Medicine, Moscow Healthcare Department</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2017</year></pub-date><volume>13</volume><issue>3</issue><fpage>35</fpage><lpage>47</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тимербаев В.Х., Драгунов А.В., Конохов П.В., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Тимербаев В.Х., Драгунов А.В., Конохов П.В.</copyright-holder><copyright-holder xml:lang="en">Timerbaev V.H., Dragunov A.V., Konokhov P.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/1591">https://www.reanimatology.com/rmt/article/view/1591</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: провести анализ состояния кислородного баланса у пострадавших с повреждения- ми органов брюшной полости и острой кровопотерей в период оперативного вмешательства и остановки кровотечения.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В исследованную группу включили 50 пострадавших — 49 мужчин и 1 женщина, возраст которых составил в среднем 33 (25,75; 44,5) года, с повреждениями органов брюшной полости, осложнившимися острой массивной кровопотерей, требующими проведения экстренного оперативного вмешательства. Тяжесть состояния пациентов по шкале ISS оценивали в 38 (27,75; 48) баллов. В работе исследовали: объем кровопотери, показатели гемоглобина, гематокрита, газового состава крови, кислородного баланса, кислотно-основного состояния, содержания электролитов, состояния тканевого метаболизма. Проводили непрерывное миниинвазивное определение показателей центральной гемодинамики. Статистическую обработку материала проводили с помощью программы SPSS (SPSS Inc., USA).</p></sec><sec><title>Результаты</title><p>Результаты. При поступлении в операционную показатели системной гемодинамики пострадавших не отражали тяжести их состояния. Имелись признаки гиповолемии при нормальных сосудистом тонусе и сердечном выбросе. В то же время, тяжесть состояния пострадавших демонстрировали показатели кислородного баланса — высокие ИПО2 и КЭO2, и низкое SvО2. Эти данные свидетельствовали о том, что в период травмы пострадавшие перенесли тяжелый эпизод дыхательной и/или циркуляторной гипоксии, которая к моменту поступления в операционную была корригирована в период оказания первичной помощи и при транспортировке. Пострадавшие имели также лабораторные признаки «кислородной задолженности». К завершению операции показатели ИПО2 оставались высокими наряду с ростом КЭO2. При этом низкие значения CvO2, PvO2, SvО2 свидетельствовали о сохраняющейся циркуляторной недостаточности.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim: to analyze the oxygen balance in patients with injuries of abdominal cavity organs and acute blood loss during surgery and arrest of bleeding.</p></sec><sec><title>Material and methods</title><p>Material and methods: the study group consisted of 50 patients (49 men and 1 woman, average age: 33 (25.75; 44.5) years) who experienced injuries of abdominal cavity organs complicated by acute massive blood loss requiring urgent surgical interventions. The severity of patients' state was 38 (27.75; 48) by ISS scoring. The study examined the following parameters: the blood loss volume, hemoglobin (Hg) level, hematocrit (HCT), blood gases, oxygen balance, acid-base balance, electrolyte levels, and the tissue metabolism status. A continuous minimally invasive monitoring of central hemodynamics parameters was performed. The statistical data processing was per- formed using the SPSS software (SPSS Inc., USA).</p></sec><sec><title>Results</title><p>Results: the central hemodynamics parameters did not reflect the severity of patients' state at their admission into an operating room. The signs of hypovolemia were observed along with normal vascular tone and cardiac out- put. At the same time, such parameters of oxygen balance as high VO2I and О2ER, as well as low SvО2 indicated the severity of patients' state. These data demonstrated that patients experienced a severe episode of respiratory or circulatory hypoxia during trauma, which had been corrected during first aid treatment and transportation by patient's admission into the operating room, so patients presented lab test findings of «oxygen debt». The VO2I values remained high in addition to the increase in О2ER values by the end of the surgery. However, low CvO2, PvO2, and SvО2 values indicated the persisting circulatory hypoxia.</p></sec><sec><title>Conclusion</title><p>Conclusion: All patients with postoperative complications were admitted into the operating room with already existing impairment of oxygen delivery. The patients did not recover from shock, the low cardiac efficiency was the main reason for its persistence. The correlation between postoperative lethal outcomes and the value of cardiac index (CI) at the end of surgery in this group of patients was demonstrated. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>кислородный баланс</kwd><kwd>кислородная задолженность</kwd><kwd>острая кровопотеря</kwd><kwd>циркуляторная недостаточность</kwd><kwd>гипоксия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>oxygen balance</kwd><kwd>oxygen debt</kwd><kwd>acute blood loss</kwd><kwd>circulatory insufficiency</kwd><kwd>hypoxia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Валетова В.В., Ермолов А.С., Тимербаев В.Х., Драгунов А.В. Влияние интраоперационной инфузионно-трансфузионной терапии на летальность больных с массивной кровопотерей. Анестезиология и реаниматология. 2012; 2: 23–27. 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