rmtОбщая реаниматологияGeneral Reanimatology1813-97792411-7110FSBI "SRIGR" RAMS10.15360/1813-9779-2018-3-68-81rmt-1692Research ArticleОБЗОРЫ И КРАТКИЕ СООБЩЕНИЯREVIEWS & SHORT COMMUNICATIONSМолекулярные биомаркеры прогнозирования неврологического исхода после внезапной остановки кровообращения (обзор)Molecular Biomarkers for Prediction of Neurological Outcome after Sudden Circulatory Arrest (Review)ГолубевА. М.GolubevA. M.КузовлевА. Н.KuzovlevA. N.artem_kuzovlev@mail.ruАнтоноваВ. В.AntonovaV. V.ЗахарченкоВ. Е.ZakharchenkoV. E.ПетроваМ. В.PetrovaM. V.ГречкоА. В.GrechkoA. V.НИИ общей реаниматологии им. В. А. Неговского ФНКЦ РРРоссияV. A. Negovsky Research Institute of General Reanimatology, Federal Research and Clinical Center of Intensive Care Medicine and RehabilitologyRussian FederationФедеральный научно-клинический центр реаниматологии и реабилитологииРоссияFederal Research and Clinical Center of Intensive Care Medicine and RehabilitologyRussian FederationФедеральный научно-клинический центр реаниматологии и реабилитологии; Российский университет дружбы народовРоссияFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology; Peoples' Friendship University of RussiaRussian Federation2018020720181436881Copyright © Голубев А.М., Кузовлев А.Н., Антонова В.В., Захарченко В.Е., Петрова М.В., Гречко А.В., 20182018Голубев А.М., Кузовлев А.Н., Антонова В.В., Захарченко В.Е., Петрова М.В., Гречко А.В.Golubev A.M., Kuzovlev A.N., Antonova V.V., Zakharchenko V.E., Petrova M.V., Grechko A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.reanimatology.com/rmt/article/view/1692

Цель обзора 81-й публикации является обсуждение современной отечественной и зарубежной доказательной базы по прогнозированию неврологических исходов после ВОК с использованием молекулярных биомаркеров. В обзоре рассмотрели современное состояние проблемы неврологических исходов после внезапной остановки кровообращения, принципиальные лечебные мероприятия, позволяющие улучшить данные исходы и существующие в настоящее время методы диагностики и прогнозирования неврологических исходов после внезапной остановки кровообращения: клинические, лабораторные и инструментальные. Подробно обсуждена доказательная база возможности использования молекулярных биомаркеров в постреанимационном периоде. 

The purpose of this review of the 81 publications is to discuss the current national and international data on the prediction of neurological outcomes after sudden circulatory arrest (SCA) using molecular biomarkers. The review discusses the current state of the problem of neurological outcomes after a sudden circulatory arrest, the principal therapeutic measures to improve these outcomes and currently available clinical, laboratory, and instrumental methods of diagnosis and prediction of neurological outcomes after a sudden circulatory arrest. 

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The authors declare that there are no conflicts of interest present.