<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2018-5-16-24</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-1709</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ ПРАКТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL PRACTICE</subject></subj-group></article-categories><title-group><article-title>Объемная капнография как способ оценки эффективности альвеолярной вентиляции в клинической практике</article-title><trans-title-group xml:lang="en"><trans-title>Volumetric Сapnography As a Tool for Evaluation of Alveolar Ventilation Effectiveness in Clinical Practice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торок</surname><given-names>П.</given-names></name><name name-style="western" xml:lang="en"><surname>Török</surname><given-names>P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павол Торок </p><p>Клиника анестезиологии и интенсивной медицины, Клиника кардиологии</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p><p>Медицинский факультет</p><p>040 11, г. Кошице, ул. SNP, д. 1 </p></bio><bio xml:lang="en"><p>Pavol Török</p><p>Clinic of Anaesthesiology and Intensive Medicin,</p><p>Clinic of cardiology</p><p>8 Ondavská Str., 040 11 Košice </p><p> Faculty of Medicine</p><p>1 SNP Str., Košice</p></bio><email xlink:type="simple">torokp@t-zones.sk</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Депта</surname><given-names>Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Depta</surname><given-names>F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p></bio><bio xml:lang="en"><p>Filip Depta </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Донич</surname><given-names>В.</given-names></name><name name-style="western" xml:lang="en"><surname>Donic</surname><given-names>V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Медицинский факультет, Институт физиологии человека, медицина сна</p><p>040 11, г. Кошице, ул. SNP, д. 1 </p></bio><bio xml:lang="en"><p>Viliam Doniс </p><p>Faculty of Medicine</p><p>Institute of Human Physiology, Sleep medicine</p><p>1 SNP Str., Košice</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Носаль</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nosál’</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p></bio><bio xml:lang="en"><p>Martin Nosál’ </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Имрэч</surname><given-names>Ш.</given-names></name><name name-style="western" xml:lang="en"><surname>Imrecze</surname><given-names>S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p></bio><bio xml:lang="en"><p>Štefan Imrecze </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Беньова</surname><given-names>Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Benová</surname><given-names>J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p></bio><bio xml:lang="en"><p>Janka Benová </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галкова</surname><given-names>К.</given-names></name><name name-style="western" xml:lang="en"><surname>Galková</surname><given-names>K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Факультет социальных наук и здравоохранения</p><p>г. Нитра, ул. Краскова, д. 1 </p></bio><bio xml:lang="en"><p>Katarína Galková </p><p>Faculty of Social Sciences and Health Care</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пауликова</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Paulíková</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p><p>г. Кошице, ул. Растиславова, д. 43 </p><p> </p></bio><bio xml:lang="en"><p>Monika Paulíková </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Берешик</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Berešík</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p><p>Военная больница, клиника анестезии и интенсивной медицины</p><p>г. Ружомберок, ул. Грабовская, д. 1 </p></bio><bio xml:lang="en"><p>Marián Berešík </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p><p>Military hospital, Clinic of anaesthesia and intensive medicine</p><p>1 Hrabovská Str., Ružomberok</p><p> </p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Янкайова</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Jankajová</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника кардиологии</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p><p>Медицинский факультет</p><p>040 11, г. Кошице, ул. SNP, д. 1 </p></bio><bio xml:lang="en"><p>Monika Jankajová </p><p>Clinic of cardiology</p><p>8 Ondavská Str., 040 11 Košice </p><p>Faculty of Medicine</p><p>1 SNP Str., Košice</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Паулины</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Paulíny</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Клиника анестезиологии и интенсивной медицины</p><p>040 11, г. Кошице, ул. Ондавска, д. 8 </p><p>Госпиталь Дерера</p><p>г. Братислава, ул. Лимбова, д. 1  </p></bio><bio xml:lang="en"><p>Matúš Paulíny </p><p>Clinic of Anaesthesiology and Intensive Medicin</p><p>8 Ondavská Str., 040 11 Košice </p><p>Dérer`s Hospital</p><p>1 Limbová Str., Bratislava</p></bio><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Восточно-Словацкий институт кардиоваскулярных болезней;&#13;
Университет Сафарика</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>East Slovakian Institute of Cardiovascular Diseases;&#13;
Safarik University</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Восточно-Словацкий институт кардиоваскулярных болезней</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>East Slovakian Institute of Cardiovascular Diseases</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Университет Сафарика</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>Safarik University</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Университет Константина Философа</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>Constantine Philosopher University</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Восточно-Словацкий институт кардиоваскулярных болезней;&#13;
Восточно-Словацкий онкологический институт</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>East Slovakian Institute of Cardiovascular Diseases</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>Восточно-Словацкий институт кардиоваскулярных болезней;&#13;
Католический университет</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>East Slovakian Institute of Cardiovascular Diseases;&#13;
Catholic university</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>Восточно-Словацкий институт кардиоваскулярных болезней;&#13;
Словацкий университет здоровья</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>East Slovakian Institute of Cardiovascular Diseases;&#13;
Slovak health university</institution><country>Slovakia</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2018</year></pub-date><volume>14</volume><issue>5</issue><fpage>16</fpage><lpage>24</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Торок П., Депта Ф., Донич В., Носаль М., Имрэч Ш., Беньова Я., Галкова К., Пауликова М., Берешик М., Янкайова М., Паулины М., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Торок П., Депта Ф., Донич В., Носаль М., Имрэч Ш., Беньова Я., Галкова К., Пауликова М., Берешик М., Янкайова М., Паулины М.</copyright-holder><copyright-holder xml:lang="en">Török P., Depta F., Donic V., Nosál’ M., Imrecze S., Benová J., Galková K., Paulíková M., Berešík M., Jankajová M., Paulíny M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/1709">https://www.reanimatology.com/rmt/article/view/1709</self-uri><abstract><p>Цель исследования — сравнить взаимосвязь между объемом мертвого пространства и дыхательным объемом (VD/VT) методом объемной капнографии (VCap) в режимах искусственной вентиляции легких с управляемым давлением (PCV) и поддержкой давлением (PSV) в послеоперационном периоде.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В обсервационное, проспективное исследование методом случайного выбора включили 30 пациентов из отделения сердечно-сосудистой хирургии, перенесших операцию аортокоронарного шунтирования (АКШ) с экстракорпоральным кровообращением. Пациентов подключали к системе вентиляции легких сразу при поступлении в отделение интенсивной терапии. Затем проводили мониторинг VD/VT, продукции CO2 (VECO2), а также параметров вентиляции. Параметры вентиляции в режимах с управляемым давлением (PCV) и поддержкой давлением (PSV) статистически оценивали</p></sec><sec><title>Результаты</title><p>Результаты. Не выявили достоверных различий концентрации CO2 во выдыхаемом воздухе (ETCO2) между режимами PCV и PSV (p=NS), хотя как VECO2, так и минутная вентиляция (MV) возрастали в режиме PSV (p&lt;0,01). Отношение VD/VT в режиме PSV было ниже, чем в режиме PCV. Газообмен, представленный альвеолярной вентиляцией (VA), был лучше в режиме PSV (p&lt;0,01). Показатель VA был также выше в режиме PSV (p&lt;0,05). Расчетное отношение VD/VT различалось между режимами PCV и PSV (p&lt;0,01).</p></sec><sec><title>Заключение</title><p>Заключение. Объемная капнография (VCap) является средством мониторинга эффективности обмена CO2. Отмечали снижение VD/VT с улучшением альвеолярной вентиляции (VA) в режиме PSV. VCap представляется подходящим методом регулирования протективной вентиляции легких.</p></sec></abstract><trans-abstract xml:lang="en"><p>The purpose of the study was to compare the relationship between the dead space volume and tidal volume (VD/VT) using volumetric capnography (VCap) during pressure controlled (PCV) and pressure supported (PSV) ventilation mode in the postoperative period.</p><sec><title>Materials and methods</title><p>Materials and methods. 30 randomly assigned cardiac surgical patients undergoing CABG (coronary artery bypass grafting) using ECC (extracorporeal circuit) were included in an observational, prospective study. Patients were connected to the ventilator immediately after ICU admission. After that, monitoring VD/VT, CO2 production (VECO2) as well as ventilation parameters was carried out. The parameters during PCV and PSV mode were statistically evaluated using t-test.</p></sec><sec><title>Results</title><p>Results. Expiratory CO2 (ETCO2) concentration were not significantly different in both PCV or PSV (p=NS), although both VECO2 and minute ventilation (MV) increased during PSV mode (p&lt;0.01). VD/VT in PSV mode was lower than in PCV. Gas exchange represented by alveolar ventilation (VA) was better during PSV (p&lt;0.01). VA was also higher during PSV (p&lt;0.05). The calculated VD/VT ratio differed between PCV and PSV mode (p&lt;0.01).</p></sec><sec><title>Conclusion</title><p>Conclusion. VCap represents a tool for monitoring of CO2 exchange effectivness. We registered a decrease in VD/VT with improved alveolar ventilation (VA) in PSV mode. VCap seems to be a suitable instrument for adjustment of protective lung ventilation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ИВЛ</kwd><kwd>объемная капнография (VCap)</kwd><kwd>вентиляция с управляемым давлением (PCV)</kwd><kwd>вентиляция с контролем давления (PSV)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>MV</kwd><kwd>volumetric capnography (VCap)</kwd><kwd>pressure controlled ventilation</kwd><kwd>pressure supported ventilation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">C…andík P., Rybár D., Sabol F., Kolesár A., Saladiak S., Imrecze Š., Ben…ová J., Galková K. Influence of ALV parameters during anaesthesia on mechanical energy absorbed by lungs. Anesteziologie a Intenzivni Medicina. 2016; 5 (2): 67-70. ISSN 1339-0155</mixed-citation><mixed-citation xml:lang="en">C…andík P., Rybár D., Sabol F., Kolesár A., Saladiak S., Imrecze Š., Ben…ová J., Galková K. Influence of ALV parameters during anaesthesia on mechanical energy absorbed by lungs. Anesteziologie a Intenzivni Medicina. 2016; 5 (2): 67-70. ISSN 1339-0155</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Tusman G., Sipmann F.S., Bohm S.H. Rationale of dead space measurement by volumetric capnography. Anesth. Analg. 2012; 114 (4): 866-874. DOI: 10.1213/ANE.0b013e318247f6cc. PMID: 22383673</mixed-citation><mixed-citation xml:lang="en">Tusman G., Sipmann F.S., Bohm S.H. Rationale of dead space measurement by volumetric capnography. Anesth. Analg. 2012; 114 (4): 866-874. DOI: 10.1213/ANE.0b013e318247f6cc. PMID: 22383673</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Tusman G., Gogniat E., Böhm S.H., Scandurra A., Suarez-Sipmann F., Torroba A., Casella F., Giannasi S., Roman E.S. Reference values for volumetric capnography-derived non-invasive parameters in healthy individuals. J. Clin. Monit. Comput. 2013; 27 (3): 281-288. DOI: 10.1007/s10877-013-9433-x. PMID: 23389294</mixed-citation><mixed-citation xml:lang="en">Tusman G., Gogniat E., Böhm S.H., Scandurra A., Suarez-Sipmann F., Torroba A., Casella F., Giannasi S., Roman E.S. Reference values for volumetric capnography-derived non-invasive parameters in healthy individuals. J. Clin. Monit. Comput. 2013; 27 (3): 281-288. DOI: 10.1007/s10877-013-9433-x. PMID: 23389294</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Bohr C. Ueber die Lungenathmung. Acta Physiol. 1891; 2 (1): 236–268. DOI: 10.1111/j.1748-1716.1891.tb00581.x</mixed-citation><mixed-citation xml:lang="en">Bohr C. Ueber die Lungenathmung. Acta Physiol. 1891; 2 (1): 236–268. DOI: 10.1111/j.1748-1716.1891.tb00581.x</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Robertson H.T. Dead space: the physiology of wasted ventilation. Eur. Respir. J. 2015; 45 (6): 1704–1716. DOI: 10.1183/09031936.00137614. PMID: 25395032</mixed-citation><mixed-citation xml:lang="en">Robertson H.T. Dead space: the physiology of wasted ventilation. Eur. Respir. J. 2015; 45 (6): 1704–1716. DOI: 10.1183/09031936.00137614. PMID: 25395032</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Fowler W.S. Lung function studies; the respiratory dead space. Am. J. Physiol. 1948; 154 (3): 405–416. DOI: 10.1152/ajplegacy.1948.154.3.405. PMID: 18101134</mixed-citation><mixed-citation xml:lang="en">Fowler W.S. Lung function studies; the respiratory dead space. Am. J. Physiol. 1948; 154 (3): 405–416. DOI: 10.1152/ajplegacy.1948.154.3.405. PMID: 18101134</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Fletcher R., Jonson B., Cumming G., Brew J. The concept of deadspace with special reference to the single breath test for carbon dioxide. Br. J. Anaesth. 1981; 53 (1): 77–88. DOI: 10.1093/bja/53.1.77. PMID: 6779846</mixed-citation><mixed-citation xml:lang="en">Fletcher R., Jonson B., Cumming G., Brew J. The concept of deadspace with special reference to the single breath test for carbon dioxide. Br. J. Anaesth. 1981; 53 (1): 77–88. DOI: 10.1093/bja/53.1.77. PMID: 6779846</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Maisch S., Reissmann H., Fuellekrug B., Weismann D., Rutkowski T., Tusman G., Böhm S.H. Compliance and dead space fraction indicate an optimal level of positive end-expiratory pressure after recruitment in anesthetized patients. Anesth. Analg. 2008; 106 (1): 175–181. DOI: 10.1213/01.ane.0000287684.74505.49. PMID: 18165575</mixed-citation><mixed-citation xml:lang="en">Maisch S., Reissmann H., Fuellekrug B., Weismann D., Rutkowski T., Tusman G., Böhm S.H. Compliance and dead space fraction indicate an optimal level of positive end-expiratory pressure after recruitment in anesthetized patients. Anesth. Analg. 2008; 106 (1): 175–181. DOI: 10.1213/01.ane.0000287684.74505.49. PMID: 18165575</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tusman G., Böhm S.H., Suarez-Sipmann F. Dead space during one-lung ventilation. Curr. Opin. Anaesthesiol. 2015; 28 (1): 10–17. DOI: 10.1097/ACO.0000000000000153. PMID: 25517622</mixed-citation><mixed-citation xml:lang="en">Tusman G., Böhm S.H., Suarez-Sipmann F. Dead space during one-lung ventilation. Curr. Opin. Anaesthesiol. 2015; 28 (1): 10–17. DOI: 10.1097/ACO.0000000000000153. PMID: 25517622</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Hubble C.L., Gentile M.A., Tripp D.S., Craig D.M., Meliones J.N., Cheifetz I.M. Deadspace to tidal volume ratio predicts successful extubation in infants and children. Crit. Care Med. 2000; 28 (6): 2034–2040. DOI: 10.1097/00003246-200006000-00059. PMID: 10890660</mixed-citation><mixed-citation xml:lang="en">Hubble C.L., Gentile M.A., Tripp D.S., Craig D.M., Meliones J.N., Cheifetz I.M. Deadspace to tidal volume ratio predicts successful extubation in infants and children. Crit. Care Med. 2000; 28 (6): 2034–2040. DOI: 10.1097/00003246-200006000-00059. PMID: 10890660</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Sinha P., Soni N. Comparison of volumetric capnography and mixed expired gas methods to calculate physiological dead space in mechanically ventilated ICU patients. Intensive Care Med. 2012; 38 (10): 1712-1717. DOI: 10.1007/s00134-012-2670-5. PMID: 22893221</mixed-citation><mixed-citation xml:lang="en">Sinha P., Soni N. Comparison of volumetric capnography and mixed expired gas methods to calculate physiological dead space in mechanically ventilated ICU patients. Intensive Care Med. 2012; 38 (10): 1712-1717. DOI: 10.1007/s00134-012-2670-5. PMID: 22893221</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">C…andík P., Rybár D., Nosá M., Saladiak S., Imrecze Š., Ben…ová J., Galková K., Paulíková M. Volumetric kapnography. Anesteziologie a Intenzivni Medicina. 2018; 29 (7). in press. ISSN: 1214-2158</mixed-citation><mixed-citation xml:lang="en">C…andík P., Rybár D., Nosá M., Saladiak S., Imrecze Š., Ben…ová J., Galková K., Paulíková M. Volumetric kapnography. Anesteziologie a Intenzivni Medicina. 2018; 29 (7). in press. ISSN: 1214-2158</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Doorduin J., Nollet J.L., Vugts M.P., Roesthuis L.H., Akankan F., van der Hoeven J.G., van Hees H.W., Heunks L.M. Assessment of dead-space ventilation in patients with acute respiratory distress syndrome: a prospective observational study. Crit. Care. 2016; 20 (1): 121-128. DOI: 10.1186/s13054-016-1311-8. PMID: 27145818</mixed-citation><mixed-citation xml:lang="en">Doorduin J., Nollet J.L., Vugts M.P., Roesthuis L.H., Akankan F., van der Hoeven J.G., van Hees H.W., Heunks L.M. Assessment of dead-space ventilation in patients with acute respiratory distress syndrome: a prospective observational study. Crit. Care. 2016; 20 (1): 121-128. DOI: 10.1186/s13054-016-1311-8. PMID: 27145818</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Siobal M.S., Ong H., Valdes J., Tang J. Calculation of physiologic dead space: comparison of ventilator volumetric capnography to measurements by metabolic analyzer and volumetric CO2 monitor. Respir. Care. 2013; 58 (7): 1143-1151. DOI: 10.4187/respcare.02116. PMID: 23232740</mixed-citation><mixed-citation xml:lang="en">Siobal M.S., Ong H., Valdes J., Tang J. Calculation of physiologic dead space: comparison of ventilator volumetric capnography to measurements by metabolic analyzer and volumetric CO2 monitor. Respir. Care. 2013; 58 (7): 1143-1151. DOI: 10.4187/respcare.02116. PMID: 23232740</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">C…andík P., Drbjáková E., Lakatoš I., Toya P., Šalantay J. Comparison of efficacy of CPAP and high-frequency jet ventilation by the nasopharyngeal mask (VFDV-M) in the treatment of lung edema. Anesteziologie a Intenzivni Medicina. 2005; 16: 284-290. ISSN: 1214-2158</mixed-citation><mixed-citation xml:lang="en">C…andík P., Drbjáková E., Lakatoš I., Toya P., Šalantay J. Comparison of efficacy of CPAP and high-frequency jet ventilation by the nasopharyngeal mask (VFDV-M) in the treatment of lung edema. Anesteziologie a Intenzivni Medicina. 2005; 16: 284-290. ISSN: 1214-2158</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Eriksson L., Wollmer P., Olsson C.G., Albrechtsson U., Larusdottir H., Nilsson R., Sjögren A., Jonson B. Diagnosis of pulmonary embolism based upon alveolar dead space analysis. Chest. 1989; 96 (2): 357–362. DOI: 10.1378/chest.96.2.357. PMID: 2752819</mixed-citation><mixed-citation xml:lang="en">Eriksson L., Wollmer P., Olsson C.G., Albrechtsson U., Larusdottir H., Nilsson R., Sjögren A., Jonson B. Diagnosis of pulmonary embolism based upon alveolar dead space analysis. Chest. 1989; 96 (2): 357–362. DOI: 10.1378/chest.96.2.357. PMID: 2752819</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Böhm S.H., Maisch S., von Sandersleben A., Thamm O., Passoni I., Martinez Arca J., Tusman G. The effects of lung recruitment on the Phase III slope of volumetric capnography in morbidly obese patients. Anesth. Analg. 2009; 109 (1): 151–159. DOI: 10.1213/ane.0b013e31819bcbb5. PMID: 19535705</mixed-citation><mixed-citation xml:lang="en">Böhm S.H., Maisch S., von Sandersleben A., Thamm O., Passoni I., Martinez Arca J., Tusman G. The effects of lung recruitment on the Phase III slope of volumetric capnography in morbidly obese patients. Anesth. Analg. 2009; 109 (1): 151–159. DOI: 10.1213/ane.0b013e31819bcbb5. PMID: 19535705</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Tusman G., Groisman I., Fiolo F.E., Scandurra A., Arca J.M., Krumrick G., Böhm S.H., Sipmann F.S. Noninvasive monitoring of lung recruitment maneuvers in morbidly obese patients: the role of pulse oximetry and volumetric capnography. Anesth. Analg. 2014; 118 (1): 137–144. DOI: 10.1213/01.ane.0000438350.29240.08. PMID: 24356163</mixed-citation><mixed-citation xml:lang="en">Tusman G., Groisman I., Fiolo F.E., Scandurra A., Arca J.M., Krumrick G., Böhm S.H., Sipmann F.S. Noninvasive monitoring of lung recruitment maneuvers in morbidly obese patients: the role of pulse oximetry and volumetric capnography. Anesth. Analg. 2014; 118 (1): 137–144. DOI: 10.1213/01.ane.0000438350.29240.08. PMID: 24356163</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Blanch L., Lucangelo U., Lopez-Aguilar J., Fernandez R., Romero P.V. Volumetric capnography in patients with acute lung injury: effects of positive endexpiratory pressure. Eur. Respir. J. 1999; 13 (5): 1048–1054. DOI: 10.1034/j.1399-3003.1999.13e19.x. PMID: 10414403</mixed-citation><mixed-citation xml:lang="en">Blanch L., Lucangelo U., Lopez-Aguilar J., Fernandez R., Romero P.V. Volumetric capnography in patients with acute lung injury: effects of positive endexpiratory pressure. Eur. Respir. J. 1999; 13 (5): 1048–1054. DOI: 10.1034/j.1399-3003.1999.13e19.x. PMID: 10414403</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Fengmei G., Jin C., Songqiao L., Congshan Y., Yi Y. Dead space fraction changes during PEEP titration following lung recruitment in patients with ARDS. Respir. Care. 2012; 57 (10): 1578–1585. DOI: 10.4187/respcare. 01497. PMID: 22417650</mixed-citation><mixed-citation xml:lang="en">Fengmei G., Jin C., Songqiao L., Congshan Y., Yi Y. Dead space fraction changes during PEEP titration following lung recruitment in patients with ARDS. Respir. Care. 2012; 57 (10): 1578–1585. DOI: 10.4187/respcare. 01497. PMID: 22417650</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Hermely A., Jakubová M., Šalantay J., C…andík P., Sopko I., Májek M., Cocherová J., Török P. Non-invasive airway cleansing with application of expulsion effect of HFJV (High Frequency Jet Ventilation). Obshchaya Reanimatologiya = General Reanimatology. 2010; 6 (6): 71-78. DOI: 10.15360/1813-9779-2010-6-71</mixed-citation><mixed-citation xml:lang="en">Hermely A., Jakubová M., Šalantay J., C…andík P., Sopko I., Májek M., Cocherová J., Török P. Non-invasive airway cleansing with application of expulsion effect of HFJV (High Frequency Jet Ventilation). Obshchaya Reanimatologiya = General Reanimatology. 2010; 6 (6): 71-78. DOI: 10.15360/1813-9779-2010-6-71</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Verschuren F., Sanchez O., Righini M., Heinonen E., Le Gal G., Meyer G., Perrier A., Thys F. Volumetric or time-based capnography for excluding pulmonary embolism in outpatients? J. Thromb. Haemost. 2010; 8 (1): 60–67. DOI: 10.1111/j.1538-7836.2009.03667.x. PMID: 19874457</mixed-citation><mixed-citation xml:lang="en">Verschuren F., Sanchez O., Righini M., Heinonen E., Le Gal G., Meyer G., Perrier A., Thys F. Volumetric or time-based capnography for excluding pulmonary embolism in outpatients? J. Thromb. Haemost. 2010; 8 (1): 60–67. DOI: 10.1111/j.1538-7836.2009.03667.x. PMID: 19874457</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Unzueta C., Tusman G., Suarez-Sipmann F., Böhm S., Moral V. Alveolar recruitment improves ventilation during thoracic surgery: a randomized controlled trial. Br. J. Anaesth. 2012; 108 (3): 517–524. DOI: 10.1093/bja/aer415. PMID: 22201185</mixed-citation><mixed-citation xml:lang="en">Unzueta C., Tusman G., Suarez-Sipmann F., Böhm S., Moral V. Alveolar recruitment improves ventilation during thoracic surgery: a randomized controlled trial. Br. J. Anaesth. 2012; 108 (3): 517–524. DOI: 10.1093/bja/aer415. PMID: 22201185</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
