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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2021-6-33-41</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-2157</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FOR PRACTIONER</subject></subj-group></article-categories><title-group><article-title>Влияние пневмоперитонеума под различным давлением на показатели легочной механики и удовлетворенность хирурга при лапароскопической холецистэктомии</article-title><trans-title-group xml:lang="en"><trans-title>The Effects of Different Pressure Pneumoperitoneum on the Pulmonary Mechanics and Surgical Satisfaction in the Laparoscopic Cholecystectomy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кючюкёзташ</surname><given-names>Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Küçüköztaş</surname><given-names>B.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Üniversite Cad. №: 9 Борнова — 35100, Турция </p></bio><bio xml:lang="en"><p>Üniversite Cad. No: 9 Bornova — 35100, Turkey </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ийиликчи</surname><given-names>Л.</given-names></name><name name-style="western" xml:lang="en"><surname>İyilikçi</surname><given-names>L.</given-names></name></name-alternatives><bio xml:lang="ru"><p> İnciraltı Mah. Mithatpaşa Cad. №: 1606 Sok. İnciraltı — 35340 Измир, Турция </p></bio><bio xml:lang="en"><p> İnciraltı Mah. Mithatpaşa Cad. No: 1606 Sok. İnciraltı — 35340 İzmir, Turkey </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озбилгин</surname><given-names>С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ozbilgin</surname><given-names>S.</given-names></name></name-alternatives><bio xml:lang="ru"><p> İnciraltı Mah. Mithatpaşa Cad. №: 1606 Sok. İnciraltı — 35340 Измир, Турция </p></bio><bio xml:lang="en"><p>İnciraltı Mah. Mithatpaşa Cad. No: 1606 Sok. İnciraltı — 35340 İzmir, Turkey</p></bio><email xlink:type="simple">ozbilginsule@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Озбилгин</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ozbilgin</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p> İnciraltı Mah. Mithatpaşa Cad. №: 1606 Sok. İnciraltı — 35340 Измир, Турция </p></bio><bio xml:lang="en"><p> İnciraltı Mah. Mithatpaşa Cad. No: 1606 Sok. İnciraltı — 35340 İzmir, Turkey </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Унек</surname><given-names>Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Ünek</surname><given-names>T.</given-names></name></name-alternatives><bio xml:lang="ru"><p> İnciraltı Mah. Mithatpaşa Cad. №: 1606 Sok. İnciraltı — 35340 Измир, Турция </p></bio><bio xml:lang="en"><p> İnciraltı Mah. Mithatpaşa Cad. No: 1606 Sok. İnciraltı — 35340 İzmir, Turkey </p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эллидокуз</surname><given-names>Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Ellidokuz</surname><given-names>H.</given-names></name></name-alternatives><bio xml:lang="ru"><p> İnciraltı Mah. Mithatpaşa Cad. №: 1606 Sok. İnciraltı — 35340 Измир, Турция </p></bio><bio xml:lang="en"><p> İnciraltı Mah. Mithatpaşa Cad. No: 1606 Sok. İnciraltı — 35340 İzmir, Turkey </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университет Эге, медицинский факультет, кафедра анестезиологии и интенсивной терапии</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Ege University, School of Medicine, Department of Anesthesiology and Intensive Care</institution><country>Turkey</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Университет Докуз Эйлул, медицинский факультет, кафедра анестезиологии и интенсивной терапии</institution><country>Турция</country></aff><aff xml:lang="en"><institution>Dokuz Eylul University, School of Medicine, Department of Anesthesiology and Intensive Care</institution><country>Turkey</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>12</month><year>2021</year></pub-date><volume>17</volume><issue>6</issue><fpage>33</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кючюкёзташ Б., Ийиликчи Л., Озбилгин С., Озбилгин М., Унек Т., Эллидокуз Х., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Кючюкёзташ Б., Ийиликчи Л., Озбилгин С., Озбилгин М., Унек Т., Эллидокуз Х.</copyright-holder><copyright-holder xml:lang="en">Küçüköztaş B., İyilikçi L., Ozbilgin S., Ozbilgin M., Ünek T., Ellidokuz H.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/2157">https://www.reanimatology.com/rmt/article/view/2157</self-uri><abstract><p>При лапароскопической хирургии в зависимости от объема пневмоперитонеума и положения пациента происходят изменения дыхания, гемодинамики и метаболизма.Цель исследования — оценить влияние повышения внутрибрюшного давления на основе пневмоперитонеума с применением CO2 при лапароскопических операциях на гемодинамические и дыхательные параметры, а также удовлетворенность хирурга и обзор операционного поля.Материалы и методы. В данное проспективное исследование включили 116 пациентов I–III класса ASA в возрасте 18–70 лет, перенесших лапароскопическую холецистэктомию. Проанализировали данные 104 пациентов. Пациентов разделили на две группы: группу низкого давления (&lt;12 мм рт. ст., НД), n=53, и группу стандартного давления (&gt;13 мм рт. ст., СД), n=51. В качестве метода обезболивания в обеих группах применяли тотальную внутривенную анестезию. Во всех группах использовали стандартный и TOF-мониторинг. Используемые методы анестезии в обеих группах документировали. До, во время и после инсуффляции газа в брюшную полость регистрировали параметры вентиляции и гемодинамические показатели. Адекватность пневмоперитонеума, обзор органов ЖКТ и операционного поля оценивал и регистрировал оперирующий хирург.Результаты. Значимых различий в насыщении кислородом периферической крови между группами НД и СД не выявили, с учетом дыхательного объема, частоты дыхательных движений, содержания СО2 в конце выдоха, среднего и пикового инспираторного давления, а также минутной вентиляции. При сравнении гемодинамических показателей, сразу после интубации и перед экстубацией трахеи отметили, что в группе НД значения систолического, диастолического и среднего артериального давления были выше. Значимых различий в частоте сердечных сокращений в исследуемые периоды между группами не наблюдали. Не отмечали и значимых различий между группами с точки зрения удовлетворенности хирургическим вмешательством и обзором операционного поля.Заключение. Пневмоперитонеум с низким давлением обеспечивает эффективную механику дыхания и стабильную гемодинамику при лапароскопической холецистэктомии. Кроме того, подобный пневмоперитонеум обеспечивает хирургу достаточное пространство для манипуляций. Анестезиологическое пособие (общая внутривенная анестезия в сочетании с нервно-мышечной блокадой) при использовании пневмоперитонеума с низким давлением обеспечивает хорошую визуализацию операционного поля.</p></abstract><trans-abstract xml:lang="en"><p>Objectives. Inspiratory, hemodynamic and metabolic changes occur in laparoscopic surgery depending on pneumoperitoneum and patient position. This study aims to evaluate the effects of intra-abdominal pressure increase based on CO2 pneumoperitoneum in laparoscopic operations on hemodynamic parameters and respiratory dynamics and satisfaction of surgeon and operative view.Materials and Methods. A total of 116 consecutive, prospective, ASA class I–III cases aged 18–70 years undergoing laparoscopic cholecystectomy were enrolled in this study. Data of 104 patients were analysed. Patients were divided into two groups as the group Low Pressure (&lt;12 mmHg) (Group LP) (n=53) and the group Standard Pressure (&gt;13 mmHg) (Group SP) (n=51). In this study administration of general anesthesia used total intravenous anaesthesia in both groups. All groups had standard and TOF monitorization applied. The anaesthesia methods used in both groups were recorded. Before, during and after peritoneal insufflation, the peroperative ventilation parameters and hemodynamic parameters were recorded. The adequacy of pneumoperitoneum, gastric and the operative view were evaluated by the operating surgeon and recorded.Results. The peripheral oxygen saturation showed no significant difference between the low and standard pressure pneumoperitoneum in view of tidal volume, respiratory rate, end tidal CO2, mean and peak inspiratory pressure, and minute ventilation values. In terms of hemodynamics, when values just after intubation and before extubation were compared, it was observed that in the LP group systolic, diastolic and mean blood pressure values were higher. In terms of heart rate, no significant difference was observed in determined periods between groups. There was no significant difference between the groups in terms of surgical satisfaction and vision.Conclusion. Low pressure pneumoperitoneum provides effective respiratory mechanics and stable hemodynamics for laparoscopic cholecystectomy. It also provides the surgeon with sufficient space for hand manipulations. Anaesthetic method, TIVA and neuromuscular blockage provided good surgery vision with low pressure pneumoperitoneum.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лапароскопическая холецистэктомия</kwd><kwd>пневмоперитонеум</kwd><kwd>операционное поле</kwd><kwd>удовлетворенность операцией</kwd><kwd>низкое давление</kwd><kwd>глубокая нервно-мышечная блокада</kwd></kwd-group><kwd-group xml:lang="en"><kwd>laparoscopic cholecystectomy</kwd><kwd>pneumoperitoneum</kwd><kwd>surgical vision</kwd><kwd>surgery satisfaction</kwd><kwd>low pressure</kwd><kwd>deep neuromuscular blockage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bittner R. The standard of laparoscopic cholecystectomy. Langenbecks Arch Surg. 2004; 389: 157–163. DOI: 10.1007/s00423-004-0471-1. PMID: 15188083</mixed-citation><mixed-citation xml:lang="en">Bittner R. The standard of laparoscopic cholecystectomy. Langenbecks Arch Surg. 2004; 389: 157–163. DOI: 10.1007/s00423-004-0471-1. PMID: 15188083</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Gin E., Lowen D., Tacey M., Hodgson R. Reduced Laparoscopic Intraabdominal Pressure During Laparoscopic Cholecystectomy and Its Effect on Post-operative Pain: a Double-Blinded Randomised Control Trial. J Gastrointest Surg. 2021 Feb 9. DOI: 10.1007/s11605-021-04919-0. PMID: 33565010</mixed-citation><mixed-citation xml:lang="en">Gin E., Lowen D., Tacey M., Hodgson R. Reduced Laparoscopic Intraabdominal Pressure During Laparoscopic Cholecystectomy and Its Effect on Post-operative Pain: a Double-Blinded Randomised Control Trial. J Gastrointest Surg. 2021 Feb 9. DOI: 10.1007/s11605-021-04919-0. PMID: 33565010</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Raval A.D., Deshpande S., Koufopoulou M., Rabar S., Neupane B., Iheanacho I., Bash L.D., Horrow J., Fuchs-Buder T. The impact of intra-abdominal pressure on perioperative outcomes in laparoscopic cholecystectomy: a systematic review and network meta-analysis of randomized controlled trials. Surg Endosc. 2020; 34 (7): 2878–2890. DOI: 10.1007/s00464-020-07527-2. PMID: 32253560</mixed-citation><mixed-citation xml:lang="en">Raval A.D., Deshpande S., Koufopoulou M., Rabar S., Neupane B., Iheanacho I., Bash L.D., Horrow J., Fuchs-Buder T. The impact of intra-abdominal pressure on perioperative outcomes in laparoscopic cholecystectomy: a systematic review and network meta-analysis of randomized controlled trials. Surg Endosc. 2020; 34 (7): 2878–2890. DOI: 10.1007/s00464-020-07527-2. PMID: 32253560</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Halldestam I., Enell E.L., Kullman E., Borch K. Development of symptoms and complications in individuals with asymptomatic gallstones. The British Journal of Surgery. 2004; 91 (6): 734–8. DOI: 10.1002/bjs.4547. PMID: 15164444</mixed-citation><mixed-citation xml:lang="en">Halldestam I., Enell E.L., Kullman E., Borch K. Development of symptoms and complications in individuals with asymptomatic gallstones. The British Journal of Surgery. 2004; 91 (6): 734–8. DOI: 10.1002/bjs.4547. PMID: 15164444</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Attili A.F., De Santis A., Capri R., Repice A.M., Maselli S. The natural history of gallstones: The GREPCO experience. The GREPCO group. Hepatology. 1995; 21 (3): 655–660. DOI: 10.1002/hep.1840210309. PMID: 7875663</mixed-citation><mixed-citation xml:lang="en">Attili A.F., De Santis A., Capri R., Repice A.M., Maselli S. The natural history of gallstones: The GREPCO experience. The GREPCO group. Hepatology. 1995; 21 (3): 655–660. DOI: 10.1002/hep.1840210309. PMID: 7875663</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">NIH. NIH consensus statement on gallstones and laparoscopic cholecystectomy. http://consensus.nih.gov/1992/1992GallstonesLaparoscopy090html.htm 1992</mixed-citation><mixed-citation xml:lang="en">NIH. NIH consensus statement on gallstones and laparoscopic cholecystectomy. http://consensus.nih.gov/1992/1992GallstonesLaparoscopy090html.htm 1992</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Gurusamy K.S., Samraj K., Davidson B.R. Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy. The Cochrane Cochrane Database of Systematic Reviews 2009: 2; 1–50. DOI: 10.1002/14651858.CD007060.pub2. PMID: 19370671.</mixed-citation><mixed-citation xml:lang="en">Gurusamy K.S., Samraj K., Davidson B.R. Low pressure versus standard pressure pneumoperitoneum in laparoscopic cholecystectomy. The Cochrane Cochrane Database of Systematic Reviews 2009: 2; 1–50. DOI: 10.1002/14651858.CD007060.pub2. PMID: 19370671.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Russell R.C. General surgery: Biliary surgery. BMJ. 1993; 307 (6914): 1266–9. DOI: 10.1136/bmj.307.6914.1266. PMID: 8281063.</mixed-citation><mixed-citation xml:lang="en">Russell R.C. General surgery: Biliary surgery. BMJ. 1993; 307 (6914): 1266–9. DOI: 10.1136/bmj.307.6914.1266. PMID: 8281063.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Dexter S.P.L, Martin I.G., Marton J., McMahon M.J. Long operation and the risk of complications from laparoscopic cholecystectomy. The British Journal of Surgery. 1997; 84: (4): 464–466. PMID: 9112893.</mixed-citation><mixed-citation xml:lang="en">Dexter S.P.L, Martin I.G., Marton J., McMahon M.J. Long operation and the risk of complications from laparoscopic cholecystectomy. The British Journal of Surgery. 1997; 84: (4): 464–466. PMID: 9112893.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Sarli L., Costi R. Prospective randomized trial of lowpressure pneumoperitoneum for reduction of shoulder-tip pain following laparoscopy. The British Journal of Surgery 2000; 87 (9): 1161–1165. DOI: 10.1046/j.1365-2168.2000.01507.x. PMID: 10971421</mixed-citation><mixed-citation xml:lang="en">Sarli L., Costi R. Prospective randomized trial of lowpressure pneumoperitoneum for reduction of shoulder-tip pain following laparoscopy. The British Journal of Surgery 2000; 87 (9): 1161–1165. DOI: 10.1046/j.1365-2168.2000.01507.x. PMID: 10971421</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Goel A., Gupta S., Bhagat T.S., Garg P. Comparative Analysis of Hemodynamic Changes and Shoulder Tip Pain Under Standard Pressure Versus Low-pressure Pneumoperitoneum in Laparoscopic Cholecystectomy. Euroasian J Hepatogastroenterol. 2019; 9 (1): 5–8. DOI: 10.5005/jp-journals-10018-1287. PMID: 31988859</mixed-citation><mixed-citation xml:lang="en">Goel A., Gupta S., Bhagat T.S., Garg P. Comparative Analysis of Hemodynamic Changes and Shoulder Tip Pain Under Standard Pressure Versus Low-pressure Pneumoperitoneum in Laparoscopic Cholecystectomy. Euroasian J Hepatogastroenterol. 2019; 9 (1): 5–8. DOI: 10.5005/jp-journals-10018-1287. PMID: 31988859</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Beylacq L., Bordes M., Semjen F., Cross A.-M. The I-gel, a single-use supraglottic airway device with a non-inflatable cuff and an esophageal vent: an observational study in children. Acta Anaesthesiol Scand 2009; 53: 376–379. DOI: 10.1111/j.1399-6576.2008.01869.x. PMID: 19243322.</mixed-citation><mixed-citation xml:lang="en">Beylacq L., Bordes M., Semjen F., Cross A.-M. The I-gel, a single-use supraglottic airway device with a non-inflatable cuff and an esophageal vent: an observational study in children. Acta Anaesthesiol Scand 2009; 53: 376–379. DOI: 10.1111/j.1399-6576.2008.01869.x. PMID: 19243322.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Williams M.T., Rice I., Ewen S.P., Elliott S.M. A comparison of the effect of two anaesthetic techniques on surgical conditions during gynaecological laparoscopy. Anaesthesia. 2003; 58 (6): 574–578. DOI: 10.1046/j.1365-2044.2003.03150.x. PMID: 12846625</mixed-citation><mixed-citation xml:lang="en">Williams M.T., Rice I., Ewen S.P., Elliott S.M. A comparison of the effect of two anaesthetic techniques on surgical conditions during gynaecological laparoscopy. Anaesthesia. 2003; 58 (6): 574–578. DOI: 10.1046/j.1365-2044.2003.03150.x. PMID: 12846625</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Khaitan L., Apelgren K., Hunter J., Traverso L.W. A report on the Society of American Gastrointestinal Endoscopic Surgeons (SAGES) outcomes initaitive. Surg Endosc. 2003; 17: 65–70. DOI: 10.1007/s00464-002-8844-4. PMID: 12469242</mixed-citation><mixed-citation xml:lang="en">Khaitan L., Apelgren K., Hunter J., Traverso L.W. A report on the Society of American Gastrointestinal Endoscopic Surgeons (SAGES) outcomes initaitive. Surg Endosc. 2003; 17: 65–70. DOI: 10.1007/s00464-002-8844-4. PMID: 12469242</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kelly M.D. Laparoscopic retrograde (fundus first) cholecystectomy. BMC Surgery. 2009; 9: 19–27. DOI: 10.1111/j.1528-1167.2009.02291.x. PMID: 19761450.</mixed-citation><mixed-citation xml:lang="en">Kelly M.D. Laparoscopic retrograde (fundus first) cholecystectomy. BMC Surgery. 2009; 9: 19–27. DOI: 10.1111/j.1528-1167.2009.02291.x. PMID: 19761450.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Singla S., Mittal G., Mittal R. Pain Management after Laparoscopic Cholecystectomy-A Randomized Prospective Trial of Low Pressure and Standard Pressure Pneumoperitoneum. J Clin Diagn Res. 2014; 8 (2): 92–94. PMID: 24701492. DOI: 10.7860/JCDR/2014/7782.4017</mixed-citation><mixed-citation xml:lang="en">Singla S., Mittal G., Mittal R. Pain Management after Laparoscopic Cholecystectomy-A Randomized Prospective Trial of Low Pressure and Standard Pressure Pneumoperitoneum. J Clin Diagn Res. 2014; 8 (2): 92–94. PMID: 24701492. DOI: 10.7860/JCDR/2014/7782.4017</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Perrakis E., Vezakis A., Velimezis G., Savanis G., Deverakis S., Antoniades J., Sagkana E. Randomized comparison between different insufflation pressures for laparoscopic cholecystectomy. Surgical Laparoscopy Endoscopy &amp;Percutaneous Techniques. 2003; 13: (4): 245–249. DOI: 10.1097/00129689-200308000-00004. PMID: 12960786</mixed-citation><mixed-citation xml:lang="en">Perrakis E., Vezakis A., Velimezis G., Savanis G., Deverakis S., Antoniades J., Sagkana E. Randomized comparison between different insufflation pressures for laparoscopic cholecystectomy. Surgical Laparoscopy Endoscopy &amp;Percutaneous Techniques. 2003; 13: (4): 245–249. DOI: 10.1097/00129689-200308000-00004. PMID: 12960786</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Ibraheim O.A., Samarkandi A.H., Alshehry H., Faden A., Farouk E.O. Lactate and acid base changes during laparoscopic cholecystectomy Middle East Journal of Anesthesiology. 2006; 18: (4): 757–768. PMID: 16749570.</mixed-citation><mixed-citation xml:lang="en">Ibraheim O.A., Samarkandi A.H., Alshehry H., Faden A., Farouk E.O. Lactate and acid base changes during laparoscopic cholecystectomy Middle East Journal of Anesthesiology. 2006; 18: (4): 757–768. PMID: 16749570.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Barczynski M., Herman R.M. A prospective randomized trial on comparison of low pressure (LP) and standard-pressure (SP) pneumoperitoneum for laparoscopic cholecystectomy. Surgical Endoscopy 2003; 17 (4): 533–538. DOI: 10.1007/s00464-002-9121-2. PMID: 12582754.</mixed-citation><mixed-citation xml:lang="en">Barczynski M., Herman R.M. A prospective randomized trial on comparison of low pressure (LP) and standard-pressure (SP) pneumoperitoneum for laparoscopic cholecystectomy. Surgical Endoscopy 2003; 17 (4): 533–538. DOI: 10.1007/s00464-002-9121-2. PMID: 12582754.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Barrio J., Errando C.L., García-Ramón J., Sellés R., San Miguel G., Gallego J. Influence of depth of neuromuscular blockade on surgical conditions during low-pressure pneumoperitoneum laparoscopic cholecystectomy: A randomized blinded study. J Clin Anesth. 2017; 42: 26–30. DOI: 10.1016/j.jclinane.2017.08.005. PMID: 28803124</mixed-citation><mixed-citation xml:lang="en">Barrio J., Errando C.L., García-Ramón J., Sellés R., San Miguel G., Gallego J. Influence of depth of neuromuscular blockade on surgical conditions during low-pressure pneumoperitoneum laparoscopic cholecystectomy: A randomized blinded study. J Clin Anesth. 2017; 42: 26–30. DOI: 10.1016/j.jclinane.2017.08.005. PMID: 28803124</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Gerges F.J., Kanazi G.E., Jabbour-Khoury S.I. Anesthesia for laparoscopy: a review. J Clinl Anesth. 2006; 18 (1): 67–78. DOI: 10.1016/j.jclinane.2005.01.013. PMID: 16517337</mixed-citation><mixed-citation xml:lang="en">Gerges F.J., Kanazi G.E., Jabbour-Khoury S.I. Anesthesia for laparoscopy: a review. J Clinl Anesth. 2006; 18 (1): 67–78. DOI: 10.1016/j.jclinane.2005.01.013. PMID: 16517337</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Odeberg-Wernerman S. Laparoscopic surgery – effects on circulatory and respiratory physiology: an overview. Eur J Surg Suppl. 2000; 585: 4–11. PMID: 10885548</mixed-citation><mixed-citation xml:lang="en">Odeberg-Wernerman S. Laparoscopic surgery – effects on circulatory and respiratory physiology: an overview. Eur J Surg Suppl. 2000; 585: 4–11. PMID: 10885548</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Makinen M.T., Yli-Hankala A. Respiratory compliance during laparoscopic hiatal and hernia repair. Can J Anaesth. 1998; 45 (9): 865–870. DOI: 10.1007/BF03012221. PMID: 9818110.</mixed-citation><mixed-citation xml:lang="en">Makinen M.T., Yli-Hankala A. Respiratory compliance during laparoscopic hiatal and hernia repair. Can J Anaesth. 1998; 45 (9): 865–870. DOI: 10.1007/BF03012221. PMID: 9818110.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Luiz T., Huber T., Hartung H.J. Ventilatory changes during laparoscopic cholecystectomy. Anaesthesist. 1992; 41 (9): 520–526. DOI: 10.1007/BF03012221. PMID: 9818110.</mixed-citation><mixed-citation xml:lang="en">Luiz T., Huber T., Hartung H.J. Ventilatory changes during laparoscopic cholecystectomy. Anaesthesist. 1992; 41 (9): 520–526. DOI: 10.1007/BF03012221. PMID: 9818110.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Kendall A.P., Bhatt S., Oh T.E. Pulmonary consequences of carbondioxide insufflation for laparoscopic cholecystectomies. Anaesthesia. 1995; 50 (4): 286–289.</mixed-citation><mixed-citation xml:lang="en">Kendall A.P., Bhatt S., Oh T.E. Pulmonary consequences of carbondioxide insufflation for laparoscopic cholecystectomies. Anaesthesia. 1995; 50 (4): 286–289.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Makinen M-T., Yli-Hankala A. The effect of laparoscopic cholecystectomy on respiratory compliance as determined by continuous spirometry. J. Clin Anesth. 1996; 8: 119–122. DOI: 10.1111/j.1365-2044.1995.tb04600.x. PMID: 7747841.</mixed-citation><mixed-citation xml:lang="en">Makinen M-T., Yli-Hankala A. The effect of laparoscopic cholecystectomy on respiratory compliance as determined by continuous spirometry. J. Clin Anesth. 1996; 8: 119–122. DOI: 10.1111/j.1365-2044.1995.tb04600.x. PMID: 7747841.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Rishimani A.S., Gautam S.C. Hemodynamic and Respiratory Changes During Laparoscopic Cholecystectomy with High and Reduced Intraabdominal Pressure. Surgical Laparoscopy and Endoscopy. 1996; 6: (3): 201–204. PMID: 8743363.</mixed-citation><mixed-citation xml:lang="en">Rishimani A.S., Gautam S.C. Hemodynamic and Respiratory Changes During Laparoscopic Cholecystectomy with High and Reduced Intraabdominal Pressure. Surgical Laparoscopy and Endoscopy. 1996; 6: (3): 201–204. PMID: 8743363.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Joris J., Noirot D.P., Legrand M.J., Jacquet N.J., Lamy M.L. Hemodynamic changes during laparoscopic cholcystectomy. Anesth Analg. 1993; 76: 1067–1071. PMID: 8743363.</mixed-citation><mixed-citation xml:lang="en">Joris J., Noirot D.P., Legrand M.J., Jacquet N.J., Lamy M.L. Hemodynamic changes during laparoscopic cholcystectomy. Anesth Analg. 1993; 76: 1067–1071. PMID: 8743363.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Marshall R.L., Jepson P.R.J., Devie I.T, Scott B. Circulatory effects of peritoneal insufflation with nitrousoxide. Br J Anaesth. 1992; 44: 1183–1187. DOI: 10.1093/bja/44.11.1183. PMID: 4647113.</mixed-citation><mixed-citation xml:lang="en">Marshall R.L., Jepson P.R.J., Devie I.T, Scott B. Circulatory effects of peritoneal insufflation with nitrousoxide. Br J Anaesth. 1992; 44: 1183–1187. DOI: 10.1093/bja/44.11.1183. PMID: 4647113.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Dubois Phileppe E., Putz L., Jamart J., Marotta M.-L.; Gourdin M., Donnez O. Deep neuromuscular block improves surgical conditions during laparoscopic hysterectomy: A randomised controlled trial. European Journal of Anaesthesiology. 2014; 31: (8): 430–436. DOI: 10.1097/EJA.0000000000000094. PMID: 24809482.</mixed-citation><mixed-citation xml:lang="en">Dubois Phileppe E., Putz L., Jamart J., Marotta M.-L.; Gourdin M., Donnez O. Deep neuromuscular block improves surgical conditions during laparoscopic hysterectomy: A randomised controlled trial. European Journal of Anaesthesiology. 2014; 31: (8): 430–436. DOI: 10.1097/EJA.0000000000000094. PMID: 24809482.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Martini C.H., Boon M., Bevers R.F., Aarts L.P., Dahan A. Evaluation of surgical conditions during laparoscopic surgery in patients with moderate vs deep neuromuscular block. Br J Anaesth. 2014; 112 (3): 498–505. DOI: 10.1093/bja/aet377. PMID: 24240315.</mixed-citation><mixed-citation xml:lang="en">Martini C.H., Boon M., Bevers R.F., Aarts L.P., Dahan A. Evaluation of surgical conditions during laparoscopic surgery in patients with moderate vs deep neuromuscular block. Br J Anaesth. 2014; 112 (3): 498–505. DOI: 10.1093/bja/aet377. PMID: 24240315.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Koo B.W., Oh A.Y., Seo K.S., Han J.W., Han H.S., Yoon Y.S. Randomized Clinical Trial of Moderate Versus Deep Neuromuscular Block for LowPressure Pneumoperitoneum During Laparoscopic Cholecystectomy. World J Surg. 2016; 40 (12): 2898–2903. DOI: 10.1007/s00268-016-3633-8. PMID: 27405749</mixed-citation><mixed-citation xml:lang="en">Koo B.W., Oh A.Y., Seo K.S., Han J.W., Han H.S., Yoon Y.S. Randomized Clinical Trial of Moderate Versus Deep Neuromuscular Block for LowPressure Pneumoperitoneum During Laparoscopic Cholecystectomy. World J Surg. 2016; 40 (12): 2898–2903. DOI: 10.1007/s00268-016-3633-8. PMID: 27405749</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Staehr-Rye A.K., Rasmussen L.S., Rosenberg J., Juul P., Gätke M.R. Optimized surgical space during low-pressure laparoscopy with deep neuromuscular blockade. Dan Med J. 2013; 60 (2): 579. PMID: 23461992.</mixed-citation><mixed-citation xml:lang="en">Staehr-Rye A.K., Rasmussen L.S., Rosenberg J., Juul P., Gätke M.R. Optimized surgical space during low-pressure laparoscopy with deep neuromuscular blockade. Dan Med J. 2013; 60 (2): 579. PMID: 23461992.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Ibraheim O.A., Samarkandi A.H., Alshehry H., Faden A., Farouk E.O. Lactate acid base changes during laparoscopic cholecystectomy. Mej Anesth. 2006; 18 (4): 757–768. PMID: 16749570.</mixed-citation><mixed-citation xml:lang="en">Ibraheim O.A., Samarkandi A.H., Alshehry H., Faden A., Farouk E.O. Lactate acid base changes during laparoscopic cholecystectomy. Mej Anesth. 2006; 18 (4): 757–768. PMID: 16749570.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Hasukic S. Postoperative changes in liver function tests randomized comparison of low- and high-pressure laparoscopic cholecystectomy. Surg Endosc. 2005; 19 (11): 1451–1455. DOI: 10.1007/s00464-005-0061-5. PMID: 16206003.</mixed-citation><mixed-citation xml:lang="en">Hasukic S. Postoperative changes in liver function tests randomized comparison of low- and high-pressure laparoscopic cholecystectomy. Surg Endosc. 2005; 19 (11): 1451–1455. DOI: 10.1007/s00464-005-0061-5. PMID: 16206003.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
