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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2012-3-25</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-216</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FOR PRACTIONER</subject></subj-group></article-categories><title-group><article-title>Ранняя диагностика критических постперфузионных расстройств кровообращения</article-title><trans-title-group xml:lang="en"><trans-title>Early Diagnosis of Critical Postperfusion Circulatory Disorders</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кричевский</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krichevsky</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">levkrich72@gmail.com</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рыбаков</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Rybakov</surname><given-names>V. Yu</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гусева</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Guseva</surname><given-names>O. G</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лямин</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Lyamin</surname><given-names>A. Yu</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харламова</surname><given-names>И. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Kharlamova</surname><given-names>I. E</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Магилевец</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Magilevets</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2012</year></pub-date><volume>8</volume><issue>3</issue><issue-title>Том VIII № 3 2012 г.</issue-title><fpage>25</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кричевский Л.А., Рыбаков В.Ю., Гусева О.Г., Лямин А.Ю., Харламова И.Е., Магилевец А.И., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Кричевский Л.А., Рыбаков В.Ю., Гусева О.Г., Лямин А.Ю., Харламова И.Е., Магилевец А.И.</copyright-holder><copyright-holder xml:lang="en">Krichevsky L.A., Rybakov V.Y., Guseva O.G., Lyamin A.Y., Kharlamova I.E., Magilevets A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/216">https://www.reanimatology.com/rmt/article/view/216</self-uri><abstract><p>Цель исследования — определение прогностического значения данных мониторинга гемодинамики и общего кислородного баланса в постперфузионный период кардиохирургических операций. Материал и методы. Ретроспективно обследовали 353 больных (317 мужчин, 35 женщин) в возрасте 57±0,6 лет, оперированных с искусственным кровообращением (78±6 мин), у которых был использован катетер Swan-Ganz. Среди обследованных больных коронарное шунтирование (3,1±0,2 шунта) выполнили 277 больным, протезирование митрального клапана — 18, аортального клапана — 42, митрально-аортальное протезирование — 9, протезирование 1—2 (1,2±0,2) клапанов сердца с шунтированием 2±1 венечных артерий — 7. Фракция изгнания левого желудочка составила в среднем 48±0,04%. На этапе сведения грудины регистрировали параметры центральной гемодинамики и кислородного баланса. Выделили группы — выписанных из клиники и умерших в стационаре. Использовали межгрупповое сравнение показателей и анализ ROC-кривых с регистрацией значений «cut off». Результаты. В постперфузионный период факторами риска госпитальной летальности являются: среднее давление в легочной артерии более 29 мм рт. ст., давление заклинивания легочной артерии более 16 мм рт. ст., сердечный индекс менее 2,35 л/мин/м2, индекс ударного объема менее 22,7 мл/м2, индексированный транспорт кислорода ниже 315,6 мл/м2, уровень лактата крови выше 4,6 ммоль/л, потребность в дозе адреналина выше 115 нг/кг/мин. С наибольшей степенью достоверности о риске летальности говорят показатели ударной работы левого желудочка: индекс ударной работы менее 21,2 гм»‘Хм»2 и, в максимальной степени, насосный коэффициент ниже 2,8 гм»‘Хм»2/мм рт. ст. Заключение. Инвазивный мониторинг давления в малом круге кровообращения и производительности сердца в постперфузионный период позволяет объективно прогнозировать риск госпитальной летальности. Ключевые слова: кардиохирургия, катетер Swan-Ganz, сердечная недостаточность, летальность.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to define the prognostic value of hemodynamic monitoring data and overall oxygen balance in the postperfusion period of cardiosurgical operations. Subjects and methods. Three hundred and fifty-three patients (317 men, 35 women) aged 57±0.6 years, who had been operated on under extracorporeal circulation (78±6 min) with a Swan-Ganz catheter being used, were retrospectively examined. Among the examined, 277 patients had undergone coronary bypass surgery (3.1±0.2 shunts); 18, mitral valve replacement; 42, aortic valve replacement; 9, mitral and aortic valve replacement; and 7 had one-two heart valve replacement with shunting of 2±1 coronary arteries. The left ventricular ejection fraction averaged 48±0.04%. The parameters of central hemodynamics and oxygen balance were recorded when the sternum was brought together. There was a group of those who had been discharged from hospital and a group of those who had died in hospital. The authors used an intergroup comparison of parameters and an analysis of ROC curves, by recording the cut off values. Results. The postperfusion risk factors of hospital mortality were a mean pulmonary artery pressure of more than 29 mm Hg; a pulmonary artery wedge pressure of greater than 16 mm Hg; a cardiac index of less than 2.35 l/min/m2; a stroke volume index of less than 22.7 ml/m2; an indexed oxygen transport of less than 315.6 ml/ml2; a blood lactate level of higher than 4.6 mmol/l; an adrenal dose need of more than 115/ng/kg/min. Left ventricular stroke work indicators, such as a stroke work index of less than 21.2 g”‘Xm”2 and, to the maximum extent, a pump coefficient of lower than 2.8 g”‘Xm”2/mm Hg, have a high degree of accuracy in suggesting the risk of mortality. Conclusion. The invasive monitoring of pulmonary pressure and cardiac efficiency in the postperfusion period permits an objective prediction of a risk for hospital mortality. Key words: cardiosurgery, Swan-Ganz catheter, heart failure, mortality.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Eagle K. A., Guyton R A., Davidoff R. et al.</mixed-citation><mixed-citation xml:lang="en">Eagle K. A., Guyton R A., Davidoff R. et al.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Binanay C., Califf R. M., Hasselblad V. et al.Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial. JAMA 2005; 294 (13): 1625—1633.</mixed-citation><mixed-citation xml:lang="en">Binanay C., Califf R. 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