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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2023-1-34-42</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-2321</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПРАКТИКУЮЩЕМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FOR PRACTIONER</subject></subj-group></article-categories><title-group><article-title>3D ЭЭГ и клинические признаки смерти мозга. Предварительное сообщение</article-title><trans-title-group xml:lang="en"><trans-title>3D EEG and Clinical Evidence of Brain Dying. Preliminary Report</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дробный</surname><given-names>М.</given-names></name><name name-style="western" xml:lang="en"><surname>Drobný</surname><given-names>M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра анестезиологии и интенсивной терапии</p><p>03601, г. Мартин, ул. Колларова, д. 2</p></bio><bio xml:lang="en"><p>Michal Drobný</p><p>Department of Anaesthesiology and Intensive medicine</p><p>2 Kollarova Str., 03601 Martin, Slovak Republic</p></bio><email xlink:type="simple">drobny@unm.sk</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дробна Саниова</surname><given-names>Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Drobná Sániová</surname><given-names>B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра анестезиологии и интенсивной терапии</p><p>03601, г. Мартин, ул. Колларова, д. 2</p></bio><bio xml:lang="en"><p>Beata Drobná Sániová</p><p>Department of Anaesthesiology and Intensive medicine</p><p>2 Kollarova Str., 03601 Martin, Slovak Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Учнова</surname><given-names>С.</given-names></name><name name-style="western" xml:lang="en"><surname>Učňová</surname><given-names>S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра анестезиологии и интенсивной терапии</p><p>03601, г. Мартин, ул. Колларова, д. 2</p></bio><bio xml:lang="en"><p>Silvia Učňová</p><p>Department of Anaesthesiology and Intensive medicine</p><p>2 Kollarova Str., 03601 Martin, Slovak Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соболова</surname><given-names>Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Sobolová</surname><given-names>G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра анестезиологии и интенсивной терапии</p><p>03601, г. Мартин, ул. Колларова, д. 2</p></bio><bio xml:lang="en"><p>Gabriela Sobolová</p><p>Department of Anaesthesiology and Intensive medicine</p><p>2 Kollarova Str., 03601 Martin, Slovak Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Койш</surname><given-names>Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Koyš</surname><given-names>R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кафедра анестезиологии и интенсивной терапии</p><p>03601, г. Мартин, ул. Колларова, д. 2</p></bio><bio xml:lang="en"><p>Richard Koyš</p><p>Department of Anaesthesiology and Intensive medicine</p><p>2 Kollarova Str., 03601 Martin, Slovak Republic</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мачадо</surname><given-names>К.</given-names></name><name name-style="western" xml:lang="en"><surname>Machado</surname><given-names>C.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гавана</p></bio><bio xml:lang="en"><p>Calixto Machado</p><p>Havana</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мачадо</surname><given-names>Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Machado</surname><given-names>Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гавана</p></bio><bio xml:lang="en"><p>Yanin Machado</p><p>Havana</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Университет Коммениуса в Братиславе, Медицинский факультет Ессениуса в Мартине, Университетская клиника</institution><country>Словакия</country></aff><aff xml:lang="en"><institution>Commenius University in Bratislava, Jessenius Medical Faculty in Martin, University Hospital</institution><country>Slovakia</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Институт неврологии и нейрохирургии</institution><country>Куба</country></aff><aff xml:lang="en"><institution>Institute of Neurology and Neurosurgery</institution><country>Cuba</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>23</day><month>02</month><year>2023</year></pub-date><volume>19</volume><issue>1</issue><fpage>34</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дробный М., Дробна Саниова Б., Учнова С., Соболова Г., Койш Р., Мачадо К., Мачадо Я., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Дробный М., Дробна Саниова Б., Учнова С., Соболова Г., Койш Р., Мачадо К., Мачадо Я.</copyright-holder><copyright-holder xml:lang="en">Drobný M., Drobná Sániová B., Učňová S., Sobolová G., Koyš R., Machado C., Machado Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/2321">https://www.reanimatology.com/rmt/article/view/2321</self-uri><abstract><p>Под смертью мозга понимается обратимое или необратимое повреждение головного мозга, включая его ствол. Современные рекомендации по диагностике смерти мозга опираются на данные клинического обследования, включающие объективные признаки комы, отсутствие стволовых рефлексов и положительный тест на апноэ. Нейрофизиологическое тестирование с использованием электроэнцефалографии (ЭЭГ) и вызванных потенциалов (соматосенсорных и слуховых стволовых) могло бы помочь в окончательном диагностическом заключении о смерти мозга, но диагностическая точность указанных методов в последние годы является предметом многочисленных обсуждений. В данной статье представили результаты количественной оценки сигналов ЭЭГ с помощью трехмерного картирования мозга (3D КM) как нового инструмента выяснения взаимосвязи между  коэффициентами когерентности при поперечном и передне-заднем сканировании и «вейвлет-преобразовании», а также поставили вопрос о том, может ли визуализация репрезентативных сигналов ЭЭГ с помощью 3D КМ улучшить информативность количественной оценки сигналов ЭЭГ при определении смерти мозга.</p><p>Цель работы — предоставить последнюю информацию об имеющихся доказательных данных и нерешенных вопросах в отношении использования ЭЭГ для определения смерти мозга и инициировать дискуссию о применении ЭЭГ для повышения эффективности стратегий трансплантации.</p><sec><title>Результаты</title><p>Результаты. Проанализировали записи ЭЭГ 10 пациентов, поступивших для проведения сердечнолегочной реанимации в период с сентября 2017 г. по август 2018 г. Данные пациентки, Ж. М., 33 лет, перенесшей геморрагический шок (август 2018 г.), проанализировали подробно. Оценили динамику количественных показателей ЭЭГ по изображениям и изменения клинической картины смерти мозга до и после внутривенного введения амантадина сульфата, который применяли для оживления головного мозга. Результаты продемонстрировали способность мозга к сохранению жизнеспособности, при этом причиной биологической смерти мозга стала сердечная недостаточность.</p></sec><sec><title>Заключение</title><p>Заключение. Получили обнадеживающие данные, позволяющие предполагать возможность выживания мозга при коме и демонстрирующие способность мозга сохранять такое функциональное состояние, которое может явиться основой для успешной социальной адаптации.</p></sec></abstract><trans-abstract xml:lang="en"><p>Determination of brain dying means reversible or irreversible injury to the brain, including the brainstem. Current guidelines rely on clinical examination including the proof of coma, absent brain stem reﬂexes, and apnoea test. Neurophysiological testing using electroencephalography and evoked potentials — somatosensory evoked potentials and brainstem auditory evoked potential could have been helpful in the final diagnostic brain death conclusion, but the diagnostic accuracy of these methods in the last years has revealed controversies. Here, we present data on quantitative EEG signal evaluation (qEEG) by a 3-dimensional brain mapping (3D BM) as developing tool to clarify whether the transverse and anterior posterior coherences such as connectivity indices may demonstrate connection in transversal or anterior posterior dimensions with «wavelet transformation» and if the 3D BM visualization of the of representative EEG signals may improve informative value of EEG signals quantification when evaluating the brain dying.</p><p>The purpose of our work is to provide an update on the evidence and controversies on the use of EEG for determining brain dying and raise discussion on EEG applications to improve the transplantation program.</p><sec><title>Results</title><p>Results. We analyzed the EEG records of 10 patients admitted for cardiopulmonary resuscitation (CPR) during September, 2017 — August, 2018. Data from one patient, ŽM, 33 years old, after haemorrhagic shock (August 2018) were analyzed in details. Quantitative EEG dynamics by images and clinical course of brain dying were monitored prior and after the amantadine sulfate intravenous administration for brain revival. Data demonstrated the ability of brain to survive; the cause of final brain death was heart failure.</p></sec><sec><title>Conclusion</title><p>Conclusion. Data confirm the hope for survival of the brain in a coma and demonstrate brain capability to keep functionally optimal state as a potential for a good social adaptation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>электроэнцефалография</kwd><kwd>смерть мозга</kwd><kwd>количественная ЭЭГ</kwd><kwd>3D картирование мозга</kwd><kwd>коэффициент когерентности при продольном и поперечном сканировании</kwd><kwd>вейвлет-преобразование</kwd><kwd>реанимация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>electroencephalography</kwd><kwd>brain dying</kwd><kwd>quantitative EEG</kwd><kwd>3D brain mapping</kwd><kwd>longitudinal and transversal coherencies</kwd><kwd>wavelet transformation</kwd><kwd>resuscitation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wijdicks E.F. Brain death worldwide: accepted fact but no global consensus in diagnostic criteria. 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