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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2024-5-31-36</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-2501</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Ультразвуковое исследование поджелудочной железы у новорожденных из группы высокого риска</article-title><trans-title-group xml:lang="en"><trans-title>Pancreatic Ultrasound in High-risk Neonates</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4853-4648</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Эль-Менеза</surname><given-names>Сафаа А.</given-names></name><name name-style="western" xml:lang="en"><surname>ELMeneza</surname><given-names>Safaa A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Каир, г. Наср, 1141, 6 округ, ул. Эльмокаям Эльдайм</p></bio><bio xml:lang="en"><p>Elmokaiam Eldaym Str., 6 district, 1141 Nasr city, Cairo</p></bio><email xlink:type="simple">safaa5@hotmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хассан</surname><given-names>Наглаа Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Hassan</surname><given-names>Naglaa F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Каир, г. Наср, 1141, 6 округ, ул. Эльмокаям Эльдайм</p></bio><bio xml:lang="en"><p>Elmokaiam Eldaym Str., 6 district, 1141 Nasr city, Cairo</p></bio><email xlink:type="simple">naglakirdasa@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мохамед</surname><given-names>Аиша Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Mohamed</surname><given-names>Aisha R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Каир, г. Наср, 1141, 6 округ, ул. Эльмокаям Эльдайм</p></bio><bio xml:lang="en"><p>Elmokaiam Eldaym Str., 6 district, 1141 Nasr city, Cairo</p></bio><email xlink:type="simple">ayshamohamed@azhar.edu.eg</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Отделение педиатрии, Факультет медицины для девушек, Университет Аль-Азхар</institution><country>Египет</country></aff><aff xml:lang="en"><institution>Pediatrics department, Faculty of Medicine for Girls, Al-Azhar University</institution><country>Egypt</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Отделение лучевых методов исследования, Факультет медицины для девушек, Университет Аль-Азхар</institution><country>Египет</country></aff><aff xml:lang="en"><institution>Radiodiagnosis departments, Faculty of Medicine for Girls, Al-Azhar University</institution><country>Egypt</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2024</year></pub-date><volume>20</volume><issue>5</issue><fpage>31</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Эль-Менеза С.А., Хассан Н.Ф., Мохамед А.Р., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Эль-Менеза С.А., Хассан Н.Ф., Мохамед А.Р.</copyright-holder><copyright-holder xml:lang="en">ELMeneza S.A., Hassan N.F., Mohamed A.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/2501">https://www.reanimatology.com/rmt/article/view/2501</self-uri><abstract><p>Ультразвуковое исследование поджелудочной железы (ПЖ) применяют для оценки структуры органа и диагностики различных заболеваний. При этом опубликованных результатов анализа ультразвукового исследования ПЖ новорожденных из группы высокого риска очень мало.</p><p>Цель исследования — изучить особенности эхогенности ПЖ у новорожденных из группы высокого риска и оценить связь между паттерном эхогенности ПЖ и клиническим диагнозом.</p><sec><title>Материалы и методы</title><p>Материалы и методы. В проспективное обсервационное ультразвуковое исследование типа «случай–контроль» включили 105 новорожденных, которых разделили на две группы. В 1-ю группу (высокого риска) включили 55 пациентов отделения интенсивной терапии новорожденных, во 2-ю группу (сравнения) — 50 новорожденных, доставленных на амбулаторный прием без информации об осложнениях беременности или родов в анамнезе. Провели ультразвуковое исследование брюшной полости с акцентом на ПЖ. Эхогенность ПЖ оценивали по отношению к печени как гиперэхогенную, изоэхогенну или гипоэхогенную. </p></sec><sec><title>Результаты</title><p>Результаты. Размеры ПЖ у новорожденных обеих групп существенно не различались. У пациентов из группы высокого риска выявили значительное преобладание гиперэхогенности над гипоэхогенностью или изоэхогенностью. Установили межгрупповое различие в эхогенности ПЖ (р=0,0001). У новорожденных группы сравнения преобладала изоэхогенность ПЖ (60%), реже обнаруживали гиперэхогенность (34%) и гипоэхогенность (6%). У новорожденных из группы высокого риска чаще выявляли гиперэхогенность ПЖ (72,72%) и значительно реже — гипоэхогенность (10,9%) и изоэхогенность (16,36%). У 83,3% младенцев, рожденных от матерей, страдающих сахарным диабетом, наблюдали гипоэхогенность ПЖ. Высокую частоту гиперэхогенности (83%) в группе высокого риска отметили среди недоношенных новорожденных и переживших перинатальную асфиксию. Гипоэхогенность ПЖ встречали с равной частотой у новорожденных мальчиков и девочек (50%); изоэхогенный паттерн преобладал у девочек (77,3%) по сравнению с мальчиками (22,2%), а гиперэхогенный - чаще встречался у мальчиков (57,5%).</p></sec><sec><title>Заключение</title><p>Заключение. Оценка состояния ПЖ у новорожденных из группы высокого риска и мониторинг отдаленных исходов имеют решающее значение, особенно у детей, чьи матери страдают сахарным диабетом.</p></sec></abstract><trans-abstract xml:lang="en"><p>Pancreatic ultrasound is employed to assess the structure of the organ and diagnose various conditions. However, analyses of pancreatic images of high-risk newborn infants are scarce.</p><sec><title>Aim of the study</title><p>Aim of the study: to investigate pancreatic echogenicity in high-risk neonates and evaluate the association between pancreatic echogenicity and clinical diagnosis.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. This prospective observational case-control ultrasound study included 105 neonates admitted to the neonatal intensive care unit or outpatient. The patients were divided into two groups: group 1 (high-risk), which included 55 high-risk neonates, and group 2 (control), which included 50 neonates of comparable age with no history of high-risk pregnancy or delivery who were presented for medical consultation. Abdominal ultrasound examinations were performed, with a focus on the pancreas. Pancreatic echogenicity was classified as hyperechoic, isoechoic, or hypoechoic, relative to the liver.</p></sec><sec><title>Results</title><p>Results. No significant difference in pancreatic size was observed between the high-risk and control groups. A significant predominance of hyperechogenicity over hypoechogenicity or isoechogenicity was found in the high-risk group. A significant difference in echogenicity was found between the high-risk and control groups (P=0.0001). Neonates in the control group were more likely to have pancreatic isoechogenicity (60%) compared to hyperechogenicity (34%) or hypoechogenicity (6%). In the high-risk group, neonates had a higher frequency of pancreatic hyperechogenicity (72.72%) compared to hypoechogenicity (10.9%) or isoechogenicity (16.36%). Notably, 83.3% of infants born to diabetic mothers had a hypoechogenic pattern. Certain high-risk infants, such as preterm infants and those with perinatal asphyxia, had a higher frequency of hyperechogenicity (83.3%). The percentage of hypoechoic pattern was comparable in male and female newborns (50%); isoechoic pattern was more prevalent in females (77.3%) than in males (22.2%), while males had a more frequent hyperechoic pattern (57.5%).</p></sec><sec><title>Conclusion</title><p>Conclusion. Evaluation of the pancreas in high-risk neonates and monitoring of long-term outcomes are of critical importance, especially in the infants of diabetic mothers. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>новорожденные группы высокого риска</kwd><kwd>поджелудочная железа</kwd><kwd>ультразвуковое исследование</kwd><kwd>гиперэхогенность</kwd><kwd>изоэхогенность</kwd><kwd>гипоэхогенность</kwd><kwd>новорожденные</kwd></kwd-group><kwd-group xml:lang="en"><kwd>high-risk neonates</kwd><kwd>pancreas</kwd><kwd>ultrasound</kwd><kwd>hyperechogenicity</kwd><kwd>isoechogenicity</kwd><kwd>hypoechogenicity</kwd><kwd>neonates</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Low G., Panu A., Millo N., Leen E. Multimodality imaging of neoplastic and nonneoplastic solid lesions of the pancreas. Radiographics. 2011; 31 (4): 993–1015. DOI: 10.1148/rg.314105731. 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