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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2011-5-42</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-267</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS &amp; SHORT COMMUNICATIONS</subject></subj-group></article-categories><title-group><article-title>Механизмы вторичного повреждения нейронов при тяжелой черепно-мозговой травме (часть 2)</article-title><trans-title-group xml:lang="en"><trans-title>Mechanisms of Secondary Neuronal Damage in Severe Brain Injury (Part 2)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мороз</surname><given-names>В. В</given-names></name><name name-style="western" xml:lang="en"><surname>Moroz</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кармен</surname><given-names>Н. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Karmen</surname><given-names>N. B.</given-names></name></name-alternatives><email xlink:type="simple">n.karmen@yandex.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маевский</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mayevsky</surname><given-names>E. I.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2011</year></pub-date><volume>7</volume><issue>5</issue><issue-title>Том VII № 5 2011 г.</issue-title><fpage>42</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мороз В.В., Кармен Н.Б., Маевский Е.И., 2011</copyright-statement><copyright-year>2011</copyright-year><copyright-holder xml:lang="ru">Мороз В.В., Кармен Н.Б., Маевский Е.И.</copyright-holder><copyright-holder xml:lang="en">Moroz V.V., Karmen N.B., Mayevsky E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/267">https://www.reanimatology.com/rmt/article/view/267</self-uri><abstract><p>Обзор посвящен механизмам вторичного гипоксически-ишемического повреждения головного мозга при тяжелой черепно-мозговой травме. Приводятся новые данные по механизмам глутамат-кальциевого повреждения нейронов, и оксидантного стресса. Ключевые слова: центральная нервная система, черепно-мозговая травма, гипоксия, ишемия, глутамат-кальциевый каскад, оксидантный стресс.</p></abstract><trans-abstract xml:lang="en"><p>The review is devoted to the mechanisms of secondary hypoxic-ischemic brain injury in severe brain trauma. It gives new data on the mechanisms of glutamate- and calcium-induced neuronal damage and oxidative stress. Key words: central nervous system, brain injury, hypoxia, ischemia, glutamate-calcium cascade, oxidative stress.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Tonder N., Johansen F. F., Frederickson C. J. et al.</mixed-citation><mixed-citation xml:lang="en">Tonder N., Johansen F. F., Frederickson C. 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