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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rmt</journal-id><journal-title-group><journal-title xml:lang="ru">Общая реаниматология</journal-title><trans-title-group xml:lang="en"><trans-title>General Reanimatology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-9779</issn><issn pub-type="epub">2411-7110</issn><publisher><publisher-name>FSBI "SRIGR" RAMS</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.15360/1813-9779-2009-3-34</article-id><article-id custom-type="elpub" pub-id-type="custom">rmt-565</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГЕМОДИНАМИКА. ГИПОКСИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HEMODYNAMICS. HYPOXIA</subject></subj-group></article-categories><title-group><article-title>Мониторинг гемодинамики и транспорта кислорода при реваскуляризации миокарда на работающем сердце</article-title><trans-title-group xml:lang="en"><trans-title>Hemodynamic and Oxygen Transport Monitoring During Myocardial Revascularization on the Working Heart</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смёткин</surname><given-names>А. А.,</given-names></name><name name-style="western" xml:lang="en"><surname>Smetkin</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киров</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirov</surname><given-names>M. Yu.</given-names></name></name-alternatives><email xlink:type="simple">smkirov@atnet.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьков</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzkov</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лёнькин</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Lenkin</surname><given-names>A. I.,</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Еремеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yeremeyev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сластилин</surname><given-names>В. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Slastilin</surname><given-names>V. Yu.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бородин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Borodin</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>20</day><month>06</month><year>2009</year></pub-date><volume>5</volume><issue>3</issue><issue-title>Том V № 3 2009 г.</issue-title><fpage>34</fpage><lpage>34</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Смёткин А.А., Киров М.Ю., Кузьков В.В., Лёнькин А.И., Еремеев А.В., Сластилин В.Ю., Бородин В.В., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Смёткин А.А., Киров М.Ю., Кузьков В.В., Лёнькин А.И., Еремеев А.В., Сластилин В.Ю., Бородин В.В.</copyright-holder><copyright-holder xml:lang="en">Smetkin A.A., Kirov M.Y., Kuzkov V.V., Lenkin A.I., Yeremeyev A.V., Slastilin V.Y., Borodin V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.reanimatology.com/rmt/article/view/565">https://www.reanimatology.com/rmt/article/view/565</self-uri><abstract><p>Цель исследования — оценить влияние алгоритма, основанного на комбинации транспульмональной термодилюции и непрерывного мониторинга насыщения венозной крови кислородом, на периоперационную инфузионную терапию и коррекцию гемодинамики, а также на продолжительность послеоперационного пребывания в отделении интенсивной терапии и стационаре при аортокоронарном шунтировании без искусственного кровообращения. Материал и методы. Пациенты были рандомизированы в две группы гемодинамического мониторинга: группа обычного мониторинга (ОМ) (n=20) и группа комплексного мониторинга (КМ) (n=20). В группе ОМ терапия основывалась на показателях центрального венозного давления, среднего артериального давления (СрАД) и частоты сердечных сокращений (ЧСС). В группе КМ терапия была основана на показателях индекса внутригрудного объема крови, СрАД, ЧСС, центральной венозной сатурации (ScvO2) и сердечного индекса (СИ). Измерения проводили перед и во время операции, а также через 2, 4 и 6 часов после операции. Результаты. В группе КМ значимо чаще использовали коллоидные растворы и добутамин, что сопровождалось ростом ScvO2 и СИ в сравнении с исходным значением. Частота использования эфедрина была значимо выше в группе ОМ. Алгоритм, основанный на комплексном мониторинге, позволил сократить время достижения критериев перевода из отделения интенсивной терапии и сроки послеоперационного пребывания в стационаре, соответственно, на 15 и 25%. Выводы. Целенаправленный алгоритм, основанный на комплексном мониторинге гемодинамики и транспорта кислорода, позволяет в ранние сроки выявить нарушения гемодинамики и провести их коррекцию, что может улучшить течение раннего послеоперационного периода при аортокоро-нарном шунтировании на работающем сердце. Ключевые слова: аортокоронарное шунтирование, целенаправленная терапия, центральная венозная сатурация.</p></abstract><trans-abstract xml:lang="en"><p>Objective: to evaluate the impact of the algorithm based on a combination of transpulmonary dilution and continuous venous blood oxygen saturation monitoring on perioperative infusion therapy and hemodynamic correction and on the length of postoperative stay in an intensive care unit and at hospital after aortocoronary bypass surgery without extracorporeal circulation. Subjects and methods. The patients were randomized to two hemodynamic monitoring groups: 1) routine monitoring (RM) (n=20) and 2) complex monitoring (CM) (n=20). In the RM group, therapy was based on the values of central venous pressure, mean blood pressure (BPmean), and heart rate (HR). In the CM group, it was founded on the values of intrathoracic blood volume index, BPmean, HR, central venous saturation (ScvO2), and cardiac index (CI). Measurements were made before, during, and 2, 4, and 6 hours after surgery. Results. In the CM group, colloidal solutions and dobutamine were significantly more frequently used, which was followed by increases in ScvO2 and CI as compared with the baseline values. The frequency of use of ephedrine was significantly higher in the RM group. The algorithm based on complex monitoring reduced the time of achieving the criteria for transferring from the intensive care unit and the length of postoperative hospital stay by 15 and 25%, respectively. Conclusion. Thus, the goal-oriented algorithm based on the complex monitoring of hemodynamics and oxygen transport makes it possible to reveal hemodynamic disturbances and correct them early, which can improve an early postoperative period during aortocoronary bypass surgery on the working heart. Key words: aortocoronary bypass surgery, goal-oriented therapy, central venous saturation.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chassot P. G, van der Linden P., Zaugg M. et al.</mixed-citation><mixed-citation xml:lang="en">Chassot P. G, van der Linden P., Zaugg M. et al.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">BoldtJ.Clinical review: Hemodynamic monitoring in the intensive care unit. Crit. Care 2002; 6 (1): 52—59.</mixed-citation><mixed-citation xml:lang="en">BoldtJ.Clinical review: Hemodynamic monitoring in the intensive care unit. Crit. Care 2002; 6 (1): 52—59.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Kirov M. Y, Lenkin A. I., Kuzkov V. 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