rmtОбщая реаниматологияGeneral Reanimatology1813-97792411-7110FSBI "SRIGR" RAMS10.15360/1813-9779-2009-3-65rmt-570Research ArticleПРАКТИКУЮЩЕМУ ВРАЧУFOR PRACTIONERОстрый панкреатит с точки зрения врача-интенсивистаAcute Pancreatitis in the View of an InternistPaulinyM.PaulinyM.-OndercamnM.OndercaninM-MackovaJ.MackovaJ.-20092006200953Том V № 3 2009 г.6565Copyright © Pauliny M., Ondercamn M., Mackova J., 20092009Pauliny M., Ondercamn M., Mackova J.Pauliny M., Ondercanin M., Mackova J.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.reanimatology.com/rmt/article/view/570

В статье рассматриваются основные принципы патофизиологии острого панкреатита, диагностика и лечение больных с тяжелой формой острого панкреатита. Ключевые слова: острый панкреатит, патофизиология, диагностика, лечение.

The paper considers the basic principles of the pathophysiology, as well as the diagnosis and treatment of patients with severe acute pancreatitis. Key words: acute pancreatitis, pathophysiology, diagnosis, treatment.

ReferencesBernard G. R, Artigas A., Brigham K. L. et al.Bernard G. R, Artigas A., Brigham K. L. et al.Bhatia M.Novel therapeutic targets for acute pancreatitis and associated multiple organ dysfunction syndrome. Curr. Drug Targets Inflamm Allergy 2002; 1 (4): 343—351.Bhatia M.Novel therapeutic targets for acute pancreatitis and associated multiple organ dysfunction syndrome. Curr. Drug Targets Inflamm Allergy 2002; 1 (4): 343—351.Dellinger R. P., Levy M. M, Carlet J. M. et al.Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit. Care Med. 2008; 36 (1): 296—327.Dellinger R. P., Levy M. M, Carlet J. M. et al.Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit. Care Med. 2008; 36 (1): 296—327.De Waele J. J., Hoste E, Blot S. I. et al.Intra-abdominal hypertension in patients with severe acute pancreatitis. Crit. Care 2005; 9 (4): R452—457.De Waele J. J., Hoste E, Blot S. I. et al.Intra-abdominal hypertension in patients with severe acute pancreatitis. Crit. Care 2005; 9 (4): R452—457.Esmon C. T.Inflammation and thrombosis: mutual regulation by protein C. Immunologist 1998; 6: 84—89.Esmon C. T.Inflammation and thrombosis: mutual regulation by protein C. Immunologist 1998; 6: 84—89.Gosling P.Salt of the earth or a drop in the ocean? A pathophysiological approach to fluid resuscitation. Emerg. Med. J. 2003; 20 (4): 306—315.Gosling P.Salt of the earth or a drop in the ocean? A pathophysiological approach to fluid resuscitation. Emerg. Med. J. 2003; 20 (4): 306—315.Gosling P., Czyz J, Nightingale P., Manji M.Microalbuminuria in the intensive care unit: Clinical correlates and association with outcomes in 431 patients. Crit. Care Med. 2006; 34 (8): 2158—2166.Gosling P., Czyz J, Nightingale P., Manji M.Microalbuminuria in the intensive care unit: Clinical correlates and association with outcomes in 431 patients. Crit. Care Med. 2006; 34 (8): 2158—2166.Cheatham M. L, White M. W, Sagraves S. G. et al.Abdominal perfusion pressure: a superior parameter in the assesment of intra-abdominal hypertension. J. Trauma 2000; 49 (4): 621—627.Cheatham M. L, White M. W, Sagraves S. G. et al.Abdominal perfusion pressure: a superior parameter in the assesment of intra-abdominal hypertension. J. Trauma 2000; 49 (4): 621—627.Kula R, Szturz P., Sklienka P. et al.A role for negative fluid balance in septic patients with abdominal compartment syndrome? Intensive Care Med. 2004; 30 (11): 2138—213Kula R, Szturz P., Sklienka P. et al.A role for negative fluid balance in septic patients with abdominal compartment syndrome? Intensive Care Med. 2004; 30 (11): 2138—213Kumar A., Haery C, Parrillo J. E.Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction. J. Cardiothorac. Vasc. Anesth. 2001; 15 (3): 364—376.Kumar A., Haery C, Parrillo J. E.Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction. J. Cardiothorac. Vasc. Anesth. 2001; 15 (3): 364—376.Lameire N, Vanholder R.Pathophysiologic features and prevention of human and experimental acute tubular necrosis. J. Am. Soc. Nephrol. 2001; 12 (17 Suppl.): S20—S32.Lameire N, Vanholder R.Pathophysiologic features and prevention of human and experimental acute tubular necrosis. J. Am. Soc. Nephrol. 2001; 12 (17 Suppl.): S20—S32.Lange H.Multiorgan dysfunction syndrome: how water might contribute to its progression. J. Cell Mol. Med. 2002; 6 (4): 653—660.Lange H.Multiorgan dysfunction syndrome: how water might contribute to its progression. J. Cell Mol. Med. 2002; 6 (4): 653—660.Lund H., Tonnesen H., Tonnesen M.H., Olsen O.Long-term recurrence and death rates after acute pancreatitis. Scand. J. Gastroenterol. 2006; 41 (2): 234—238.Lund H., Tonnesen H., Tonnesen M.H., Olsen O.Long-term recurrence and death rates after acute pancreatitis. Scand. J. Gastroenterol. 2006; 41 (2): 234—238.Malbrain M.L.N.G. for the CI AH study group. Incidence of intra-abdominal hypertension in the ICU and its relation with fluid balance, organ failure and 28 day mortality. Intensive Care Med. 2001; 27 (2 Suppl.): S176.Malbrain M.L.N.G. for the CI AH study group. Incidence of intra-abdominal hypertension in the ICU and its relation with fluid balance, organ failure and 28 day mortality. Intensive Care Med. 2001; 27 (2 Suppl.): S176.Mc Clave S. A., Chang W. K., Dhaliwal R., Hey land D. K.Nutrition Support in Acute Pancreatitis: A Systematic Review of the Literature. J. Parenter. Enteral Nutr. 2006; 30 (2): 143—156.Mc Clave S. A., Chang W. K., Dhaliwal R., Hey land D. K.Nutrition Support in Acute Pancreatitis: A Systematic Review of the Literature. J. Parenter. Enteral Nutr. 2006; 30 (2): 143—156.Malbrain M. L., Cheatham M. L., Kirkpatrick A. et al.Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. Intensive Care Med. 2006; 32 (11): 1722—1732.Malbrain M. L., Cheatham M. L., Kirkpatrick A. et al.Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. Intensive Care Med. 2006; 32 (11): 1722—1732.Montravers P., Chollet-Martin S., Marmuse J. P. et al.Lymphatic release of cytokines during acute lung injury complicating severe pancreatitis. Am. J. Respir. Crit. Care Med. 1995; 152 (5 Pt 1): 1527—1533.Montravers P., Chollet-Martin S., Marmuse J. P. et al.Lymphatic release of cytokines during acute lung injury complicating severe pancreatitis. Am. J. Respir. Crit. Care Med. 1995; 152 (5 Pt 1): 1527—1533.O’Leary M. J. Bihari D. J.Preventing renal failure in the critically ill. There are no magic bullets-just high quality intensive care. BMJ 2001; 322 (7300): 1437—1439.O’Leary M. J. Bihari D. J.Preventing renal failure in the critically ill. There are no magic bullets-just high quality intensive care. BMJ 2001; 322 (7300): 1437—1439.Rotondo M. F., Reilly P. M.Bleeding and coagulation complications. In: Trauma. Mattox K. L., Feliciano D. V., Moore E. E. (ed.). 4th ed. New York: McGraw-Hill; 2000. 1274—1275.Rotondo M. F., Reilly P. M.Bleeding and coagulation complications. In: Trauma. Mattox K. L., Feliciano D. V., Moore E. E. (ed.). 4th ed. New York: McGraw-Hill; 2000. 1274—1275.Scolapio J. S.Methods for Decreasing Risk of Aspiration Pneumonia in Critically Ill Patients. J. Parenter. Enteral Nutr. 2002; 26 (6): S58.Scolapio J. S.Methods for Decreasing Risk of Aspiration Pneumonia in Critically Ill Patients. J. Parenter. Enteral Nutr. 2002; 26 (6): S58.Thorevska N., Sabahi R., Upadya A. et al.Microalbuminuria in critically ill medical patients: Prevalence, predictors, and prognostic significance. Crit. Care Med. 2003; 31 (4): 1075—1081.Thorevska N., Sabahi R., Upadya A. et al.Microalbuminuria in critically ill medical patients: Prevalence, predictors, and prognostic significance. Crit. Care Med. 2003; 31 (4): 1075—1081.UK Working Party on Acute Pancreatitis. UK guidelines for the management of acute pankreatitis. Gut 2005; 54 (1): 1—9.UK Working Party on Acute Pancreatitis. UK guidelines for the management of acute pankreatitis. Gut 2005; 54 (1): 1—9.

The authors declare that there are no conflicts of interest present.