Лёгочный сурфактант и его применение при заболеваниях лёгких
https://doi.org/10.15360/1813-9779-2007-1-66-77
Аннотация
В обзоре рассмотрены современные представления о функциях легочного сурфактанта (ЛС), сделан акцент на защитных и барьерных свойствах, а также свойствах поддержания врожденного локального и адаптивного иммунитета. Проведен анализ состава коммерческих препаратов ЛС, представлены сведения о качественных и количественных нарушениях ЛС при различных видах патологии новорожденных и взрослых. Проведен детальный анализ результатов клинических испытаний различных препаратов ЛС при лечении ОРДС у взрослых. Представлены новые сведения о результатах и перспективах сурфактант-терапии бронхиальной астмы, ХОБЛ и туберкулеза легких.
Ключевые слова
легочный сурфактант,
препараты сурфактанта,
сурфактант-терапия,
ОРДС,
бронхиальная астма,
ХОБЛ,
туберкулез
Об авторе
О. А. Розенберг
Отдел медицинской биотехнологии Центрального научно-исследовательского рентгенорадиологического института Минздрава РФ, Санкт-Петербург
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Рецензия
Для цитирования:
Розенберг О.А. Лёгочный сурфактант и его применение при заболеваниях лёгких. Общая реаниматология. 2007;3(1):66-77. https://doi.org/10.15360/1813-9779-2007-1-66-77
For citation:
Rosenberg O.A. Lung Surfactant and Its Use in Lung Diseases. General Reanimatology. 2007;3(1):66-77. (In Russ.) https://doi.org/10.15360/1813-9779-2007-1-66-77
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