The Specific Features of the Course of Critical Conditions in Miners
https://doi.org/10.15360/1813-9779-2012-4-88
Abstract
Objective: to improve treatment results in miners, by studying the specific features of the course of their critical conditions caused by severe traumatic injuries, and to develop differentiated intensive therapeutic regimens for detected abnormalities. Subjects and methods. A total of 1107 subjects were examined during the study. Central hemodynamic function was explored in 371 healthy miners with various lengths of underground mining; a control group included 30 healthy volunteers unexposed to occupational hazards. Examinations were made in 386 severe brain injury victims, including 218 victims with no length of underground work and 115 injured miners with an underground work length of more than 5 years. A control group comprised 53 apparently healthy donors. One hundred and twenty-two miners with severe thermal injury were examined. A control group consisted of 39 apparently healthy volunteers. One hundred and six victims with acute respiratory distress syndrome in the presence of severe concomitant injury were examined under mechanical ventilation. Sixty-three injured miners formed a study group; a comparison group included 43 subjects with no length of underground mining. Conclusion. Upon longer exposure to occupational hazards, the prenosological changes occur in the miners' organs and systems, which display a regular phasic pattern, fit in the picture of general adjustment syndrome, and determine the specific features of critical conditions. The peculiarities of the critical conditions caused by severe traumatic injuries in miners are the early development and high frequency of complications, the more severe course and late recovery of the body's lost functions, unlike the victims unexposed to occupational hazards. Differentiated intensive therapy for critical conditions in miners with severe traumatic injuries makes it possible to improve treatment results and to reduce death rates.
About the Authors
V. V. MorozRussian Federation
Yu. A. Churlyaev
Russian Federation
S. L. Kan
Russian Federation
References
1. Tsigelnik M.I., Pavlov A.F., Trubitsin A.A. Occupational morbidity and traumatism in coal mining industry of Kuzbass. Meditsina Truda i Promyshlennaya Ekologiya. 2002; 10: 9—11.
2. Fomenko D.V., Ulanova E.V., Gromov K.G. et al. Biomedical study of the influence of coal dust as a factor of intoxication. Byul. VSNTs SO RAMN. 2006; 1 (65): 278—283. [In Russ.].
3. Lastkov D.O. The physiological and hygienic evaluation of combined impact of local vibration, noise, and warming microclimate on miners. Meditsina Truda i Promyshlennaya Ekologiya. 1998; 4: 4—8. [In Russ.].
4. Shanin V.Yu. Pathophysiology of critical conditions. Saint Petersburg: ELBI SPb.; 2003. [In Russ.].
5. Agadzhanyan V.V., Ustyantseva I.M., Pronskikh A.A. Polytrauma. Emergency care and transportation. Novosibirsk; 2008. [In Russ.].
6. Epifantseva N.N., Borshchikova T.I., Churlyaev Yu.A., Dantsiger D.G., Nikiforova N.V., Kheringson L.G. Endogenous intoxication in pulmonary complications in patients with severe brain injury. Obshchaya Reanimatologiya. 2008; 4 (3): 36—43. [In Russ.].
7. Epifantseva N.N., Borshchikova T.I., Sitnikov P.G., Churlyaev Yu.A., Ratkin I.K., Nikiforova N.V., Surzhikova G.S., Klochkova-Abelyants S.A., Averchenkova G.N. Serum markers of apoptosis in traumatic and ischemic brain injury. Obshchaya Reanimatologiya. 2009; 5 (6): 54—59. [In Russ.].
8. Epifantseva N.N., Borshchikova T.I., Churlyaev Yu.A., Ratkin I.K., Nikiforova N.V., Klochkova-Abelyants S.A., Kheringson L.G. Oxidant-antioxidant balance in severe brain injury. Obshchaya Reanimatologiya. 2010; 6 (1): 22—27. [In Russ.].
9. Churlyaev Yu.A., Verein M.Yu., Kan S.L., Grigoryev E.V., Epifantseva N.N., Aikina T.P. Acute respiratory distress syndrome in severe brain injury. Obshchaya Reanimatologiya. 2009; 5 (2): 21—26. [In Russ.].
10. Borshchikova T.I., Epifantseva N.N., Surzhikova G.S., Churlyaev Yu.A., Klochkova-Abelyants S.A., Kheringson L.G., Ekimovskikh A.V. Immune status in the acute period of severe brain injury in the development of pyoseptic complications. Obshchaya Reanimatologiya. 2010; 6 (3): 35— 42. [In Russ.].
11. Borshchikova T.I., Epifantseva N.N., Churlyaev Yu.A., Nikiforova N.V., Zhukova Ya.A., Pirogova A.I., Nikitina E.A., Ekimovskikh A.V. Proteins of the Hageman factor system in an inflammatory reaction in the acute period of severe brain injury. Obshchaya Reanimatologiya. 2010; 6 (4): 10—17. [In Russ.].
12. Kan S.L., Kosovskikh A.A., Churlyaev Yu.A., Zoloyeva O.S., Ekimovskikh A.V., Voyevodin S.V., Shleikher N.V. The microcirculatory system in critical conditions caused by abdominal sepsis. Obshchaya Reanimatologiya. 2011; 7 (4): 20—23. [In Russ.].
13. Zoloyeva O.S., Bykova E.V., Vartanyan A.R., Kan S.L., Redkokasha L.Yu., Churlyaev Yu.A., Grigoryev E.V. Functional changes in microcirculation in miners in relation to the length of underground work. Obshchaya Reanimatologiya. 2011; 7 (5): 10—14. [In Russ.].
14. Lukashev K.V. Diagnosis and intensive therapy of respiratory disorders in patients with spinal cord compression: Abstract of Cand. Med. Sci. Dissertation. Moscow, 2008. 21.
15. Vartanyan A.R. The general patterns and pathogenetic significance of central hemodynamic changes in miners: Abstract of Cand. Med. Sci. Dissertation. Kemerovo, 2008. 22. [In Russ.].
16. Vartanyan A.R., Kondrashin G.V., Budayev A.V., Vyalov D.V., Churlyaev Yu.A. Functional changes in the hemodynamics of miners. Obshchaya Reanimatologiya. 2006; 2 (1): 29—31. [In Russ.].
17. Churlyaev Yu.A., Kiselev V.N., Pronichev E.Yu., Chechenin M.G., Kan Ya.A. Functional features of external respiration in miners. Obshchaya Reanimatologiya. 2007; 3 (2): 5—9. [In Russ.].
18. Moroz V.V., Churlyaev Yu.A., Sherstobitov A.V., Martynenkov V.Ya., Redkokasha L.Yu., Sitnikov P.G., Kolyshkina N.V. Central hemodynamic function in miners with thermal injury. Obshchaya Reanimatologiya. 2008; 4 (4): 5—8. [In Russ.].
19. Nikiforova N.V. Regulatory and protective functions of the bloodbrain barrier in critical conditions in brain injury victims: Abstract of Doct. Med. Sci. Dissertation. Moscow, 2004. 46. [In Russ.].
20. Kan S.L. Specific features of bloodbrain barrier permeability abnormality in critical conditions caused by severe brain injury in miners: Abstract of Cand. Med. Sci. Dissertation. Moscow, 2006. 22. [In Russ.].
21. Sherstobitov A.V. Central hemodynamics and oxygen transport in miners with severe thermal injury: Abstract of Cand. Med. Sci. Dissertation. Moscow, 2009. 22. [In Russ.].
22. Sitnikov P.G. The hemostatic system in miners with severe brain injury: Abstract of Cand. Med. Sci. Dissertation. Moscow, 2006. 21. [In Russ.].
23. Kiselev V.N. Acute respiratory distress syndrome in miners with severe concomitant injury: Abstract of Cand. Med. Sci. Dissertation. Moscow, 2008. 22. [In Russ.].
Review
For citations:
Moroz V.V., Churlyaev Yu.A., Kan S.L. The Specific Features of the Course of Critical Conditions in Miners. General Reanimatology. 2012;8(4):88. (In Russ.) https://doi.org/10.15360/1813-9779-2012-4-88
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