Extracorporeal Treatments for Abdominal Sepsis
https://doi.org/10.15360/1813-9779-2015-5-45-66
Abstract
In spite of considerable progress in the intensive treatment of abdominal sepsis, mortality from this disease remains very high. A systemic inflammatory response to infection is characterized by the blood flow release of endotoxin and inflammatory mediators, which cause circulatory disorders and multiple organ dysfunctions. High frequency Doppler ultrasound allows dynamic estimation of tissue perfusion during efferent treatment.
Objective: to give an account of current approaches to extracorporeal treatment for abdominal sepsis in the light of urgent views on the pathogenesis of bacterial translocation and a systemic inflammatory response, as well as macrohemodynamic disorders and tissue perfusion failure.
About the Authors
E. S. Bazhina
V. A. Negovsky Research Institute of General Reanimatology 25, Petrovka St., Build. 2, Moscow 107031, Russia
Russian Federation
Russian Federation
A. V. Nikulin
V. A. Negovsky Research Institute of General Reanimatology 25, Petrovka St., Build. 2, Moscow 107031, Russia
Acad. N. N. Burdenko Main Military Clinical Hospital, Ministry of Defense of the Russian Federation 3, Gospitalnaya Sq., Moscow 105094, Russia
Russian Federation
Russian Federation
S. E. Khoroshilov
V. A. Negovsky Research Institute of General Reanimatology 25, Petrovka St., Build. 2, Moscow 107031, Russia
Acad. N. N. Burdenko Main Military Clinical Hospital, Ministry of Defense of the Russian Federation 3, Gospitalnaya Sq., Moscow 105094, Russia
Russian Federation
Russian Federation
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Bazhina E.S., Nikulin A.V., Khoroshilov S.E. Extracorporeal Treatments for Abdominal Sepsis. General Reanimatology. 2015;11(5):45-66. https://doi.org/10.15360/1813-9779-2015-5-45-66
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