Evaluation of Quality of Medical Care to Patients with the Risk of Developing Acute Kidney Injury
https://doi.org/10.15360/1813-9779-2018-3-36-45
Abstract
The purpose of the research: to analyze the quality of medical care of patients who are at risk of developing acute kidney injury.
Materials and methods. The work is based on a retrospective analysis of medical records of 140 patients with an acute kidney injury developed during their stay the intensive care units, surgical and medical units of district hospitals the Irkutsk Oblast over the period from 2012 to 2017.
Results. Inadequate assessment of the risk of an acute kidney injury was identified in 61% of patients. The most common inadequately assessed damaging factors were critical conditions (in 36% (50/140), sepsis (27% (38/140), and nephrotoxic drugs (19% (26/140). Among inadequately evaluated predisposing factors that could be managed, the following ones were most common: chronic heart disease (in 42% (59/140), dehydration/hypovolaemia (34% (47/140), chronic kidney disease (29% (41/140), and anemia (25% (35/140). In patients at risk of an acute kidney injury, an inadequate examination and inadequate maintenance therapy were found in 66% and 56% cases, respectively. Analysis of implementation of supporting therapy in patients at risk of an acute kidney injury the following misconducting events were revealed: (i) no optimal volumic and perfusion support (59% (82/140) and (ii) no cancellation of nephrotoxic and improperly prescribed drugs (31% (44/140).
Conclusions. A good quality medical care restricted only by 24% of patients at risk of an acute kidney injury developed in the ICU, surgical and medical departments of district hospitals of the Irkutsk Oblast. The development of an acute kidney injury when exposed to nephrotoxic drugs and dehydration/ hypovolemia in 14% of cases was predictable and preventable.
About the Authors
A. V. DatsRussian Federation
4, 100 Yubileyny microdistrict, 664049 Irkutsk gion w:st="on">Russia
L. S. Dats
Russian Federation
4, 100 Yubileyny microdistrict, 664049 Irkutsk gion w:st="on">Russia
References
1. Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int. Suppl. 2012; 2 (1): 1-138. DOI: 10.1038/kisup.2011.37
2. Andrusev A.M., Vatazin A.V., Gurevich K.Ya., Zakharova E.N., Zemchenkov A.Yu., Kotenko O.N., Ilyin A.P., Rei S.I., Tomilina N.A., Shilov E.M. Clinical guidelines for the diagnosis and treatment of acute renal damage. Scientific Society of Nephrologists in Russia. Moscow; 2014.
3. Hoste E.A., Clermont G., Kersten A., Venkataraman R., Angus D.C., De Bacquer D., Kellum J.A. RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: a cohort analysis. Crit. Care. 2006; 10 (3): R73. DOI: 10.1186/cc4915. PMID: 16696865
4. Uchino S., Bellomo R., Goldsmith D., Bates S., Ronco C. An assessment of the RIFLE criteria for acute renal failure in hospitalized patients. Crit. Care Med. 2006; 34: (7): 1913–1917. DOI: 10.1097/01.CCM.0000224227.70642.4F. PMID: 16715038
5. Thakar C.V., Christianson A., Freyberg R., Almenoff P., Render M.L. Incidence and outcomes of acute kidney injury in intensive care units: a Veterans Administration study. Crit. Care Med. 2009; 37 (9): 2552–2558. DOI: 10.1097/CCM.0b013e3181a5906f. PMID: 19602973
6. Joannidis M., Metnitz B., Bauer P., Schusterschitz N., Moreno R., Druml W., Metnitz P.G. Acute kidney injury in critically ill patients classified by AKIN versus RIFLE using the SAPS 3 database. Intensive Care Med. 2009; 35 (10): 1692–1702. DOI: 10.1007/s00134-009-1530-4. PMID: 19547955
7. Coca S.G., Yusuf B., Shlipak M.G., Garg A.X., Parikh C.R. Long-term risk of mortality and other adverse outcomes after acute kidney injury: a systematic review and metaanalysis. Am. J. Kidney Dis. 2009; 53 (6): 961– 973. DOI: 10.1053/j.ajkd.2008.11.034. PMID: 19346042
8. Wald R., Quinn R.R., Luo J., Li P., Scales D.C., Mamdani M.M., Ray J.G.; University of Toronto Acute Kidney Injury Research Group. Chronic dialysis and death among survivors of acute kidney injury requiring dialysis. JAMA. 2009; 302 (11): 1179–1185. DOI: 10.1001/jama.2009.1322. PMID: 19755696
9. Stewart J., Findlay G., Smith N., Kelly K., Mason M. Adding insult to injury: a review of the care of patients who died in hospital with a primary diagnosis of acute kidney injury (acute renal failure). A report by the National Confidential Enquiry into Patient Outcome and Death. http://www.ncepod.org.uk/ 2009aki.htm 2009
10. Federal Law No. 323-FZ of 21.11.2011 (as amended on 17.03.18) «On the fundamentals of protecting the health of citizens in the Russian Federation», Article 64. [In Russ.]
11. Ministry of Health Care of Russia. Order from 07.07.2015 № 422an «On the approval of criteria for assessing the quality of care». [In Russ.]
12. Ministry of Health Care of Russia. Order from 15.11.2012 № 919n «On the approval of the procedure for providing medical care to the adult population on the profile of «nephrology». [In Russ.]
13. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. Suppl. 2013; 3 (1): 1-150. DOI: 10.1038/kisup.2012.48
14. Dellinger R.P., Levy M.M., Rhodes A., Annane D., Gerlach H., Opal S.M., Sevransky J.E., Sprung C.L., Douglas I.S., Jaeschke R., Osborn Т.М., Nunnally M.E., Townsend S.R., Reinhart К., Kleinpell R.М., Angus D.C., Deutschman C.S., Machado F.R., Rubenfeld G.D., Webb S.A., Beale R.J., Vincent J.L., Moreno R.; Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit. Care Med. 2013; 41 (2): 580-637. DOI: 10.1097/ CCM.0b013e31827e83af. PMID: 23353941
15. Rhodes A., Evans L.E., Alhazzani W., Levy M.M., Antonelli M., Ferrer R., Kumar A., Sevransky J.E., Sprung C.L., Nunnally M.E., Rochwerg B., Rubenfeld G.D., Angus D.C., Annane D., Beale R.J., Bellinghan G.J., Bernard G.R., Chiche J.D., Coopersmith C., De Backer D.P., French C.J., Fujishima S., Gerlach H., Hidalgo J.L., Hollenberg S.M., Jones A.E., Karnad D.R., Kleinpell R.M., Koh Y., Lisboa T.C., Machado F.R., Marini J.J., Marshall J.C., Mazuski J.E., McIntyre L.A., McLean A.S., Mehta S., Moreno R.P., Myburgh J., Navalesi P., Nishida O., Osborn T.M., Perner A., Plunkett C.M., Ranieri M., Schorr C.A., Seckel M.A., Seymour C.W., Shieh L., Shukri K.A., Simpson S.Q., Singer M., Thompson B.T., Townsend S.R., Van der Poll T., Vincent J.L., Wiersinga W.J., Zimmerman J.L., Dellinger R.P. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit. Care Med. 2017; 45 (3): 486-552. DOI: 10.1097/CCM.0000000000002255. PMID: 28098591
16. Prowle J.R., Bellomo R. Continuous renal replacement therapy: recent advances and future research. Nat. Rev. Nephrol. 2010; 6 (9): 521–529. DOI: 10.1038/nrneph.2010.100. PMID: 20644583
17. Bouchard J., Soroko S.B., Chertow G.M., Himmelfarb J., Ikizler T.A., Paganini E.P., Mehta R.L.; Program to Improve Care in Acute Renal Disease (PICARD) Study Group. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int. 2009; 76 (4): 422–427. DOI: 10.1038/ki.2009.159. PMID: 19436332
18. Payen D., de Pont A.C., Sakr Y., Spies C., Reinhart K., Vincent J.L.; Sepsis Occurrence in Acutely Ill Patients (SOAP) Investigators. A positive fluid balance is associated with a worse outcome in patients with acute renal failure. Crit. Care. 2008; 12 (3): R74. DOI: 10.1186/cc6916. PMID: 18533029
Review
For citations:
Dats A.V., Dats L.S. Evaluation of Quality of Medical Care to Patients with the Risk of Developing Acute Kidney Injury. General Reanimatology. 2018;14(3):36-45. https://doi.org/10.15360/1813-9779-2018-3-36-45