Frequency Characteristics of Rhythm Non-Assimilation in Canine Ventricular Fibrillation
https://doi.org/10.15360/1813-9779-2010-4-58
Abstract
Ventricular fibrillation is the main cause of sudden cardiac death in many countries, including Russia; therefore to study ventricular fibrillation is an urgent problem. Objective: to study rhythm non-assimilation in canine ventricular fibrillation. Materials and methods. The author made a frequency analysis of electrocardiograms in 25 dogs with ventricular fibrillation, by applying the fast Fourier transform method. The frequency analysis was carried out in the frequency ranges corresponding to those of delta, theta, alpha, beta, and gamma rhythms of an electroencephalogram. Results. Ventricular fibrillation is characterized by rhythm non-assimilation with the oscillations being recorded on an electrocardiogram in the frequency ranges corresponding to those of delta, theta, alpha, beta, and gamma rhythms of an electroencephalogram. The proportion of oscillations in the frequency ranges of delta, theta, alpha, beta, and gamma rhythms is determined by cardiac functional mobility (lability). The latter is reduced by ischemia in ventricular fibrillation. Diminished cardiac lability in ventricular fibrillation reflects the stages of rhythm non-assimilation with a dominant and non-dominant frequency pattern naturally detectable by the frequency analysis of an electrocardiogram in the frequency ranges of delta, theta, alpha, beta, and gamma rhythms. The greater proportion of alpha, beta, and gamma rhythm frequencies in the non-dominant frequency pattern of rhythm non-assimilation in ventricular fibrillation is, the deeper cardiac lability fall is. Conclusion. The frequency analysis of an electrocardiogram in the frequency ranges of delta, theta, alpha, beta, and gamma rhythms allows the stages of rhythm non-assimilation to be objectively determined in the entire range — at all stages of ventricular fibrillation. The findings may be included into the algorithms of an automated electrocardiogram analysis, which permits objective determination of ventricular fibrillation stages in automated defibrillators. Key words: canine heart, ventricular fibrillation, rhythm non-assimilation.
References
1. Востриков В. А.
2. Бокерия Л. А., Ревишвили А. Ш., Неминущий Н. М.Имплантируемые кардиовертеры-дефибрилляторы: основное предназначение — первичная профилактика внезапной сердечной смерти. Тихоокеанский мед. журн. 2007; 1: 6—11.
3. Востриков В. А.Сердечно-легочная реанимация и неотложная кардиологическая помощь при внезапном прекращении эффективной сердечной деятельности (догоспитальный и госпитальный этапы). ч. 1. Клин. анестезиол. реаниматол. 2007; 4 (4): 2—7.
4. Гурвич Н. Л.Основные принципы дефибрилляции сердца. М.: Медицина; 1975.
5. Huizar J. F., Warren M. D., Shvedko A. G. et al.Three distinct phases of VF during global ischemia in the isolated blood-perfused pig heart. Am. J. Physiol. Heart Circ. Physiol. 2007; 293 (3): H1617—H1628.
6. Гурьянов М. И.Усвоение ритма изолированным сердцем собаки в условиях изоволюмии. Росс. физиолог. журн. им. И. М. Сеченова 2002; 88 (3): 363—371.
7. Гурьянов М. И.Усвоение ритма изолированным сердцем собаки при плавном повышении частоты стимуляции. Росс. физиолог. журн. им. И. М. Сеченова 2003; 89 (12): 1529—153
8. Ухтомский А. А.Ансамбль возбуждения и электротон. Собр. соч. в 6 томах. Л.: изд-во ЛГУ; 1950—1962. т. 6. 152—167.
9. Зенков Л. Р., Ронкин М. А.Функциональная диагностика нервных болезней. Руководство для врачей. 3-е изд. М.; 2004.
10. Zaitsev A. V., Guha P. K., Sarmast F. et al.Wavebreak formation during ventricular fibrillation in the isolated, regionally ischemic pig heart. Circ. Res. 2003; 92 (5): 546—553.
11. Koller M. L., Riccio M. L., Gilmour R. F.Dynamic restitution of action potential duration during electrical alternans and ventricular fibrillation. Am. J. Physiol. 1998; 275 (5 Pt 2): H1635—H1642.
12. Boyett M. R., Jewell B. R.Analysis of the effects of changes in rate and rhythm upon electrical activity in the heart. Prog. Biophys. Mol. Biol. 1980; 36 (1): 1—52.
13. Sanchez-MunozJ.J., Rojo-AlvarezJ. L., Garcfa-Alberola A. et al.Spectral analysis of intracardiac electrograms during induced and spontaneous ventricular fibrillation in humans. Europace 2009; 11 (3): 328—331.
14. Panfilov I., Lever N. A., Smaill B. H., Larsen P. D.Ventricular fibrillation frequency from implanted cardioverter defibrillator devices. Europace 2009; 11 (8): 1052—1056.
15. Masse S., Downar E., Chauhan V. et al.Ventricular fibrillation in myo-pathic human hearts: mechanistic insights from in vivo global endocar-dial and epicardial mapping. Am. J. Physiol. Heart Circ. Physiol. 2007; 292 (6): H2589—H2597.
16. Иванов Г. Г., Востриков В. А.Фибрилляция желудочков и желудочковые тахикардии — базовые положения и диагностические критерии. 10-я науч.-практ. конф. Диагностика и лечение нарушений регуляции сердечно-сосудистой системы. М.; 2008. 300—311.
17. Tabereaux P. B., Dosdall D. J., Ideker R. E.Mechanisms of VF maintenance: wandering wavelets, mother rotors, or foci. Heart Rhythm 2009; 6 (3): 405—415.
18. Keldermann R. H., ten Tusscher K. H., Nash M. P. et al.A computational study of mother rotor VF in the human ventricles. Am. J. Physiol. Heart Circ. Physiol. 2009; 296 (2): H370—H379.
19. Keldermann R. H., ten Tusscher K. H., Nash M. P. et al.Effect of heterogeneous APD restitution on VF organization in a model of the human ventricles. Am. J. Physiol. Heart Circ. Physiol. 2008; 294 (2): H764—H774.
20. ten Tusscher K. H., MouradА., Nash M. P. et al.Organization of ventricular fibrillation in the human heart: experiments and models. Exp. Physiol. 2009; 94 (5): 553—562.
21. Li L., Jin Q., Huang J. et al.Intramural foci during long duration fibrillation in the pig ventricle. Circ. Res. 2008; 102 (10): 1256—1264.
22. Robertson P. G., Huang J., Chen K. A. et al.Increased cycle length during long duration ventricular fibrillation is caused by decreased upstroke velocity as well as prolonged refractoriness. Heart Rhythm 2009; 6 (3): 378—384.
23. Гурьянов М. И.Способ диагностики стадий фибрилляции желудочков сердца. Патент РФ № 2373849. Приоритет от 10.06.2008. Опубл. 27.11.2009. Бюл. № 33.
Review
For citations:
Guryanov M.I. Frequency Characteristics of Rhythm Non-Assimilation in Canine Ventricular Fibrillation . General Reanimatology. 2010;6(4):58. (In Russ.) https://doi.org/10.15360/1813-9779-2010-4-58
Views:
1099
Email this article 