Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis
https://doi.org/10.15360/1813-9779-2005-6-65-69
Abstract
Objective: to determine the sensitivity and specificity of combined stress echocardiography (EchoCG) using dipyri-damole and dobutamine in diagnosing and defining the extent of stenotic coronary lesions in coronary heart disease (CHD) in a group of critically ill patients who are unable to perform a physical exercise.
Materials and methods: the study included 57 male patients with suspected acute coronary syndrome who underwent stress EchoCG using dipyridamole in high doses in combination with dobutamine, as well as coronary angiography.
Results: stress EchoCG could bring up to the diagnostic criteria in all the patients, of whom 9 patients were found at coronary angiography to have no coronary lesion, 34 and 14 patients had one- and many-vessel lesions, respectively. The sensitivity and specificity of combined stress EchoCG were significantly higher than those of EchoCG used in the diagnosis of CHD.
Conclusion: stress EchoCG using dipyridamole in combination with dobutamine is a highly informative safe noninvasive technique for diagnosing CHD, its helps to identify patients with atypical acute coronary syndrome and to form a group of patients to be subject to urgent coronarography and angiosurgical intervention. The pattern of segmental contractile disorders at the height of exercise during combined stress Echo-CG makes it possible to define the site of stenotic coronary atherosclerosis with 97.3% sensitivity and to diagnose many-vessel lesion with 100% sensitivity and 100%specificity.
About the Authors
A. Yu. Vasilyev
Department of Radiation Diagnosis, Moscow State Medical and Stomatological University, Moscow
N. N. Mikheyev
Main Clinical Hospital, Ministry of Internal Affairs of Russia, Moscow
T. P. Makarova
Main Clinical Hospital, Ministry of Internal Affairs of Russia, Moscow
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Review
For citations:
Vasilyev A.Yu., Mikheyev N.N., Makarova T.P. Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis. General Reanimatology. 2005;1(6):65-69. (In Russ.) https://doi.org/10.15360/1813-9779-2005-6-65-69
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