Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury
https://doi.org/10.15360/1813-9779-2016-4-49-56
Abstract
Objective: to identify the effectiveness of the drug Reamberin in complex intensive threatment of patients with cardiac surgery in heart fibrillation and remodeling of prosthetic heart valves and plastic defects of atrial and ventricular septa.
Reamberin according the following protocol: 400 ml in the first 6 hours of the postoperative period as an intravenous drip at a rate of 60—90 drops/min. In group 2 (control group), 26 patients received standard intensive care medication. In addition to standard clinical and laboratory tests during the study following components were quantitavile determined in blood: troponin I, lactate dehydrogenase, creatine kinase, isofractions of creatine kinase
MB, transaminases (alanine aminotransferase and aspartate aminotransferase).
Results. Treatment of patients from the main group revealed the recovery of functional parametersof the myocardium, improved dynamics of cardiac enzymes and normalization of blood acid-base status.
Conclusion. Inclusion in the complex intensive therapy of post#cardiac surgery of the Reamberin in patients experiencing heart fibrillation after the cardiopulmonary bypass followed by electrical defibrillation improved the clinical course of the early postoperative period and reduced the risk of complications and early mortality.
About the Authors
L. V. Nowicka-Usenko
Dnepropetrovsk Medical Academy of the Ministry of Health of Ukraine
Russian Federation
Russian Federation
A. V. Tsarev
Dnepropetrovsk Medical Academy of the Ministry of Health of Ukraine
Russian Federation
Russian Federation
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Review
For citations:
Nowicka-Usenko L.V., Tsarev A.V. Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury. General Reanimatology. 2016;12(4):49-56. https://doi.org/10.15360/1813-9779-2016-4-49-56
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