Preview

General Reanimatology

Advanced search

Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods

https://doi.org/10.15360/1813-9779-2011-6-53

Abstract

Objective: to optimize preoperative preparation of patients with multifocal atherosclerosis and reduced baseline left ventricular ejection fraction for coronary bypass surgery, by providing a rationale for the use of mechanical and medical circulatory support methods. Subjects and methods. Sixty-one patients with multifocal atherosclerosis, coronary heart disease (CHD), and reduced baseline left ventricular ejection fraction, who underwent coronary bypass surgery, were examined. Levosimendan was administered to 2 groups of patients: 1) 28 patients with preoperative intra-aortic balloon counterpulsation; 2) as inotropic support in 33 patients. There were central and intracardiac hemodynamic changes as evidenced by transpulmonary thermodilution and pulsed Doppler ultrasound echocardiog-raphy during different preoperative preparations. Conclusion. The use of levosimendan in patients with multifocal atherosclerosis, CHD, and planned coronary bypass surgery, by taking into account contraindications to intra-aor-tic balloon counterpulsation, makes it possible to improve central hemodynamical parameters and to reduce the degree of diastolic dysfunction, the incidence of organ dysfunctions, and the length of intensive care unit stay. Key words: coronary bypass surgery, left ventricular ejection fraction, multifocal atherosclerosis, levosimendan, intra-aortic balloon counterpulsation.

References

1. Eagle K. A, Guyton R. A, Davidoff R. et al.

2. Eagle K. A., Guyton R. A., Davidoff R. et al.ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery). Circulation 2004; 110 (14): e340—e437.

3. Кричевский Л. А., Козлов И. А.Прогнозирование сроков нормализации сердечной функции после операций с искусственным кровообращением. Общая реаниматология 2007; III (5—6): 153—156.

4. Dyub A. M., Whitlock R. P., Abouzahr L. L., Cina C. S.Preoperative intra-aortic balloon pump in patients undergoing coronary bypass surgery: a systematic review and meta-analysis. J. Card. Surg. 2008; 23 (1): 79—86.

5. Marra C., De Santo L. S., Amarelli C. et al.Coronary artery bypass grafting in patients with severe left ventricular dysfunction: a prospective randomized study on the timing of perioperative intraaortic balloon pump support. Int. J. Artif. Organs 2002; 25 (2): 141 — 146.

6. Ranucci M., Ballotta A., Castelvecchio S. et al.Perioperative heart failure in coronary surgery and timing of intra-aortic balloon pump insertion. Acta Anaesthesiol. Scand. 2010; 54 (7): 878—884.

7. Sezai A., Hata M., Niino T. et al.Continuous low-dose infusion of human atrial natriuretic peptide in patients with left ventricular dysfunction undergoing coronary artery bypass grafting: the NU-HIT (Nihon University working group study of low-dose Human ANP Infusion Therapy during cardiac surgery) for left ventricular dysfunction. J. Am. Coll. Cardiol. 2010; 55 (17): 1844—1851.

8. De Hert S. G., Lorsomradee S., vanden Eede H. et al.A randomized trial evaluating different modalities of levosimendan administration in cardiac surgery patients with myocardial dysfunction. J. Cardiothorac. Vasc. Anesth. 2008; 22 (5): 699—705.

9. Tokuda Y., Grant P. W., Wolfenden H. D. et al.Levosimendan for patients with impaired left ventricular function undergoing cardiac surgery. Interact. Cardiovasc. Thorac. Surg. 2006; 5 (3): 322—326.

10. Diez C., Silber R. E., Wachner M. et al.EuroSCORE directed intraaortic balloon pump placement in high-risk patients undergoing cardiac surgery-retrospective analysis of 267 patients. Interact. Cardiovasc. Thorac. Surg. 2008; 7 (3): 389—395.

11. ЛомиворотовВ. В., КорниловИ. А., ЧернявскийА. М. исоавт.Опыт превентивного использования внутриаортальной баллонной контрпульсации у больных с низкой фракцией выброса левого желудочка, оперированных в условиях искусственного кровообращения. Анестезиология и реаниматология 2009; 6: 51—54.

12. Santarpino G., Onorati F., Rubino A. S. et al.Preoperative intraaortic balloon pumping improves outcomes for high-risk patients in routine coronary artery bypass graft surgery. Ann. Thorac. Surg. 2009; 87 (2): 481—488.

13. Lorusso R., Gelsomino S., Carella R. et al.Impact of prophylactic intra-aortic balloon counter-pulsation on postoperative outcome in high-risk cardiac surgery patients: a multicentre, propensity-score analysis. Eur. J. Cardiothorac. Surg. 2010; 38 (5): 585—591.

14. Zangrillo A., Biondi-Zoccai G., Mizzi A. et al.Levosimendan reduces cardiac troponin release after cardiac surgery: a meta-analysis of randomized controlled studies. J. Cardiothorac. Vasc. Anesth. 2009; 23 (4): 474—478.

15. Landoni G., Mizzi A., Biondi-Zoccai G. et al.Reducing mortality in cardiac surgery with levosimendan: a meta-analysis of randomized controlled trials. J. Cardiothorac. Vasc. Anesth. 2010; 24 (1): 51—57.

16. АксельродБ. А., ТолстоваИ. А., ТрековаН. А. исоавт.Влияние предоперационной терапии левосименданом на волемический статус и сосудистый тонус у больных с хронической сердечной недостаточностью во время анестезии. Анестезиология и реаниматология 2009; 6: 46—51.

17. Еременко А. А., Колпаков П. Е., Бабаев М. А. и соавт.Применение лево-симендана у кардиохирургических больных с хронической сердечной недостаточностью. Анестезиология и реаниматология 2010; 2: 24—27.

18. Topkara V. K., Cheema F. H., Kesavaramanujam S. et al.Coronary artery bypass grafting in patients with low ejection fraction. Circulation 2005; 112 (9 Suppl): 344—350.


Review

For citations:


Grigoryev E.V., Geize A.V., Plotnikov G.P., Sizova I.N., Shukevich D.L., Sumin A.N. Preoperative Preparation of Patients with Multifocal Atherosclerosis for Coronary Bypass Surgery: Mechanical and Medical Methods . General Reanimatology. 2011;7(6):53. (In Russ.) https://doi.org/10.15360/1813-9779-2011-6-53

Views: 1264


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1813-9779 (Print)
ISSN 2411-7110 (Online)