Система гемостаза в норме и при трансплантации печени (обзор)
https://doi.org/10.15360/1813-9779-2018-5-58-84
Аннотация
Обзор посвящен проблеме нарушений в системе гемостаза и их коррекции в периоперационном периоде у пациентов, подвергающихся трансплантации печени. Обсуждаются: физиология системы гемостаза; нарушения функции свертывающей системы крови у пациентов на различных стадиях операции трансплантации печени; коррекция нарушений гемостаза во время и после ортотопической трансплантации печени. Трансплантация печени выполняется пациентам с заболеваниями печени в терминальной стадии печеночно-клеточной недостаточности. При этом изменения в системе гемостаза этих больных представляют значительный риск развития, как кровотечений, так и тромбозов во время и после трансплантации печени. Коррекция нарушений гемостаза при трансплантации печени должна проходить с учетом нозологической формы повреждения печени, механизмов развития нарушений гемостаза реципиента и этапа операции.
Об авторах
В. И. Решетняк
НИИ общей реаниматологии им. В. А. Неговского ФНКЦ РР
Россия
Россия
Василий Решетняк
107031, Москва, ул. Петровка, д. 25, стр. 2
С. В. Журавель
НИИ скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы
Россия
Россия
129090, г. Москва, Большая Сухаревская пл., д. 3
Н. К. Кузнецова
НИИ скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы
Россия
Россия
129090, г. Москва, Большая Сухаревская пл., д. 3
В. М. Писарев
НИИ общей реаниматологии им. В. А. Неговского ФНКЦ РР
Россия
Россия
107031, Москва, ул. Петровка, д. 25, стр. 2
Е. В. Клычникова
НИИ скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы
Россия
Россия
129090, г. Москва, Большая Сухаревская пл., д. 3
В. Е. Сюткин
НИИ скорой помощи им. Н. В. Склифосовского Департамента здравоохранения г. Москвы
Россия
Россия
129090, г. Москва, Большая Сухаревская пл., д. 3
Т. М. Решетняк
НИИ ревматологии им. В. А. Насоновой
Россия
Россия
115522, Москва, Каширское шоссе, д. 34А
Список литературы
1. Starzl T.E., Demetris A.J. Liver transplantation: a 31-year perspective. Chicago, London, Boca Raton, Littleton, Mass: Year book medical publishers, Inc.; 1990: 206. ISBN: 0-8151-7931-6
2. Oldenburg J., Marinova M., Müller-Reible C., Watzka M. The vitamin K cycle. Vitam. Horm. 2008; 78: 35-62. DOI: 10.1016/S00836729(07)00003-9. PMID: 18374189
3. Bandyopadhyay P.K., Garrett J.E., Shetty R.P., Keate T., Walker C.S., Olivera B.M. gamma-Glutamyl carboxylation: an extracellular posttranslational modification that antedates the divergence of molluscs, arthropods, and chordates. Proc. Natl. Acad. Sci. USA. 2002; 99 (3): 12641269. DOI: 10.1073/pnas.022637099. PMID: 11818531
4. Bandyopadhyay P.K. Vitamin K-dependent gamma-glutamylcarboxylation: an ancient posttranslational modification. Vitam. Horm. 2008; 78: 157-184. DOI: 10.1016/S0083-6729(07)00008-8. PMID: 18374194
5. Morrissey J.H. Tissue factor: a key molecule in hemostatic and nonhemostatic systems. Int. J. Hematol. 2004; 79 (2): 103-108. DOI: 10.1532/IJH97.03167. PMID: 15005335
6. Hanson S.R., Griffin J.H., Harker L.A., Kelly A.B., Esmon C.T., Gruber A. Antithrombotic effects of thrombin-induced activation of endogenous protein C in primates. J. Clin. Invest. 1993; 92 (4): 2003-2012. DOI: 10.1172/JCI116795. PMID: 8408654
7. Shaw A.W., Pureza V.S., Sligar S.G., Morrissey J.H. The local phospholipid environment modulates the activation of blood clotting. J. Biol. Chem. 2007; 282 (9): 6556-6563. DOI: 1074/jbc.M607973200. PMID: 17200119
8. Morrissey J.H., Pureza V., Davis-Harrison R.L., Sligar S.G., Ohkubo Y.Z., Tajkhorshid E. Blood clotting reactions on nanoscale phospholipid bilayers. Thromb. Res. 2008; 122 (Suppl 1): S23-S26. DOI: 10.1016/S00493848(08)70014-8. PMID: 18691494
9. Smith S.A., Morrissey J.H. Polyphosphate: a new player in the field of hemostasis. Curr. Opin. Hematol. 2014; 21 (5): 388-394. DOI: 10.1097/MOH.0000000000000069. PMID: 25010799
10. Morrissey J.H., Davis-Harrison R.L., Tavoosi N., Ke K., Pureza V., Boettcher J.M., Clay M.C., Rienstra C.M., Ohkubo Y.Z., Pogorelov T.V., Tajkhorshid E. Protein-phospholipid interactions in blood clotting. Thromb. Res. 2010; 125 (Suppl 1): S23-S25. DOI: 10.1016/j.thromres.2010.01.027. PMID: 20129649
11. Ke K., Yuan J., Morrissey J.H. Tissue factor residues that putatively interact with membrane phospholipids. PLoS One. 2014; 9 (2): e88675. DOI: 10.1371/journal.pone.0088675. PMID: 24516673
12. Tavoosi N., Smith S.A., Davis-Harrison R.L., Morrissey J.H. Factor VII and protein C arephosphatidic acid-binding proteins. Biochemistry. 2013; 52 (33): 5545-5552. DOI: 10.1021/bi4006368. PMID: 23879866
13. Morawitz P. Beiträge zur Kenntnis der Blutgerinnung. Beitr. chem. Physiol. Pathol. 1904; 5: 133-141.
14. Morawitz P. Beiträge zur Kenntnis der Blutgerinnung. 2. Mitteilung. Arch. Klin. Med. 1904; 79: 215-233.
15. Nahas L., Macfarlane R.G., Denson K.W. A study of the coagulant action of eight snake venoms. Thromb. Diath. Haemorrh. 1964; 12: 355-367. PMID: 14254694
16. Davie E.W., Ratnoff O.D. Waterfall sequence for intrinsic blood clotting. Science. 1964; 145 (3638): 1310-1312. DOI: 10.1126/science.145.3638.1310. PMID: 14173416
17. Broze G.J.Jr. Tissue factor pathway inhibitor and the current concept of blood coagulation. Blood Coagul. Fibrinolysis. 1995; 6 (Suppl 1): S7-S13. DOI: 10.1097/00001721-199506001-00002. PMID: 7647225
18. Hoffman M.A., Monroe D.M.3rd. Сell-based model of hemostasis. Thromb. Haemost. 2001; 85 (6): 958-965. PMID: 11434702
19. Stout R.W., Crawford V. Seasonal variations in fibrinogen concentrations among elderly people. Lancet. 1991; 338 (8758): 9-13. DOI: 10.1016/0140-6736(91)90004-9. PMID: 1676131
20. Stout R.W., Crawford V.L., McDermott M.J., Rocks M.J., Morris T.C. Seasonal changes in haemostatic factors in young and elderly subjects. Age Ageing. 1996; 25 (3): 256-258. DOI: 10.1093/ageing/25.3.256. PMID: 8670564
21. Hermida R.C., Calvo C., Ayala D.E., López J.E., Fernández J.R., Mojón A., Domínguez M.J., Covelo M. Seasonal variation of fibrinogen in dipper and nondipper hypertensive patients. Circulation. 2003; 108 (9): 1101-1106. DOI: 10.1161/01.CIR.0000085992.67380.7B. PMID: 12912809
22. Hall T.H., Dhir A. Anesthesia for liver transplantation. Semin. Cardiothorac. Vasc. Anesth. 2013; 17 (3): 180-194. DOI: 10.1177/108925321 3481115. PMID: 23482506
23. Palomo Sanchez J.C., Jimenez C., Moreno Gonzalez E., Garcia I., Palma F., Loinaz C., Gonzalez Ghamorro A. Effects of intraoperative blood transfusion on postoperative complications and survival after orthotopic liver transplantation. Hepatogastroenterology. 1998; 45 (22): 1026–1033. PMID: 9756002
24. Cleland S., Corredor C., Ye J.J., Srinivas C., McCluskey S.A. Massive haemorrhage inliver transplantation: сonsequences, prediction and management. World J. Transplant. 2016; 6 (2): 291-305. DOI: 10.5500/wjt.v6.i2.291. PMID: 27358774
25. Kang Y.G., Martin D.J., Marquez J., Lewis J.H., Bontempo F.A., Shaw B.W.Jr., Starzl T.E., Winter P.M. Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation. Anesth. Analg. 1985; 64 (9): 888–896. DOI: 10.1213/00000539198509000-00008. PMID: 3896028
26. Kriz N., Rinder C.S., Rinder H.M. Physiology of hemostasis: with relevance to current and future laboratory testing. Clin. Lab. Med. 2009; 29 (2): 159-174. DOI: 10.1016/j.cll.2009.06.004. PMID: 19665673
27. Rana A., Petrowsky H., Hong J.C., Agopian V.G., Kaldas F.M., Farmer D., Yersiz H., Hiatt J.R., Busuttil R.W. Blood transfusion requirement during liver transplantation is an important risk factor for mortality. J. Am. Coll. Surg. 2013; 216 (5): 902–907. DOI: 10.1016/j.jamcollsurg.2012.12.047. PMID: 23478547
28. Pereboom I.T., de Boer M.T., Haagsma E.B., Hendriks H.G., Lisman T., Porte R.J. Platelet transfusion during liver transplantation is associated with increased postoperative mortality due to acute lung injury. Anesth. Analg. 2009; 108 (4): 1083–1091. DOI: 10.1213/ane.0b013e3181948a59. PMID: 19299765
29. Steib A., Freys G., Lehmann C., Meyer C., Mahoudeau G. Intraoperative blood losses and transfusion requirements during adult liver transplantation remain difficult to predict. Can. J. Anaesth. 2001; 48 (11): 1075– 1079. DOI: 10.1007/BF03020372. PMID: 11744582
30. Massicotte L., Beaulieu D., Roy J.D., Marleau D., Vandenbroucke F., Dagenais M., Lapointe R., Roy A. MELD score and blood product requirements during liver transplantation: no link. Transplantation. 2009; 87 (11): 16891694. DOI: 10.1097/TP.0b013e3181a5e5f1. PMID: 19502961
31. Mangus R.S., Kinsella S.B., Nobari M.M., Fridell J.A., Vianna R.M., Ward E.S., Nobari R., Tector A.J. Predictors of blood product use in orthotopic liver transplantation using the piggyback hepatectomy technique. Transplant. Proc. 2007; 39 (10): 3207–3213. DOI: 10.1016/j.transproceed.2007.09.029. PMID: 18089355
32. Feng Z.Y., Jin X.D., Chen Y.Z. Predictors of massive blood transfusion in liver transplantation for patients with benign end-stage liver disease. Zhonghua Yi Xue Za Zhi. 2008; 88: 3040–3044. PMID: 19192401
33. Li C., Mi K., Wen T.F., Yan L.N., Li B., Wei Y.G., Yang J.Y., Xu M.Q., Wang W.T. Risk factors and outcomes of massive red blood cell transfusion following living donor liver transplantation. J. Dig. Dis. 2012; 13 (3): 161– 167. DOI: 10.1111/j.1751-2980.2011.00570.x. PMID: 22356311
34. Tao Y.F., Teng F., Wang Z.X., Guo W.Y., Shi X.M., Wang G.H., Ding G.S., Fu Z.R. Liver transplant recipients with portal vein thrombosis: a single center retrospective study. Hepatobiliary Pancreat. Dis. Int. 2009; 8 (1): 34–39. PMID: 19208512
35. Esmat Gamil M., Pirenne J., Van Malenstein H., Verhaegen M., Desschans B., Monbaliu D., Aerts R., Laleman W., Cassiman D., Verslype C., Van Steenbergen W., Van Pelt J., Nevens F. Risk factors for bleeding and clinical implications in patients undergoing liver transplantation. Transplant. Proc. 2012; 44 (9): 2857–2860. DOI: 10.1016/j.transproceed.2012.09.085. PMID: 23146542
36. Varotti G., Santori G., Andorno E., Morelli N., Ertreo M., Strada P., Porcile E., Casaccia M., Centanaro M., Valente U. Impact of Model for End-Stage Liver Disease score on transfusion rates in liver transplantation. Transplant. Proc. 2013; 45 (7): 2684–2688. DOI: 10.1016/j.transproceed.2013.07.006. PMID: 24034024
37. De Santis G.C., Brunetta D.M., Nardo M., Oliveira L.C., Souza F.F., Cagnolati D., Mente К.D., Sankarankutty A.K., Covas D.T., de Castro e Silva O. Preoperative variables associated with transfusion requirements in orthotopic liver transplantation. Transfus. Apher. Sci. 2014; 50 (1): 99–105. DOI: 10.1016/j.transci.2013.10.006. PMID: 24291115
38. Cywinski J.B., Alster J.M., Miller C., Vogt D.P., Parker B.M. Prediction of intraoperative transfusion requirements during orthotopic liver transplantation and the influence on postoperative patient survival. Anesth. Analg. 2014; 118 (2): 428–437. DOI: 10.1213/ANE.0b013e3182a76f19. PMID: 24445640
39. Ramos E., Dalmau A., Sabate A., Lama C., Llado L., Figueras J., Jaurrieta E. Intraoperative red blood cell transfusion in liver transplantation: influence on patient outcome, prediction of requirements, and measures to reduce them. Liver Transpl. 2003; 9 (12): 1320–1327. DOI: 10.1016/jlts.2003.50204. PMID: 14625833
40. Fan S.T., Yong B.H., Lo C.M., Liu C.L., Wong J. Right lobe living donor liver transplantation with or without venovenous bypass. Br. J. Surg. 2003; 90 (1): 48–56. DOI: 10.1002/bjs.4026. PMID: 12520574
41. Busque S., Esquivel C.O., Concepcion W., So S.K. Experience with the piggyback technique without caval occlusion in adult orthotopic liver transplantation. Transplantation. 1998; 65 (1): 77–82. DOI: 10.1097/00007890-199801150-00015. PMID: 9448148
42. Hosein Shokouh-Amiri M., Osama Gaber A., Bagous W.A., Grewal H.P., Hathaway D.K., Vera S.R., Stratta R.J., Bagous T.N., Kizilisik T. Choice of surgical technique influences perioperative outcomes in liver transplantation. Ann. Surg. 2000; 231 (6): 814–823. DOI: 10.1097/00000658200006000-00005. PMID: 10816624
43. Nishida S., Nakamura N., Vaidya A., Levi D.M., Kato T., Nery J.R., Madariaga J.R., Molina E., Ruiz P., Gyamfi A., Tzakis A.G. Piggyback technique in adult orthotopic liver transplantation: an analysis of 1067 liver transplants at a single center. HPB (Oxford). 2006; 8 (3): 182–188. DOI: 10.1080/13651820500542135. PMID: 18333273
44. Senzolo M., Burra P., Cholongitas E., Burroughs A.K. New insights into the coagulopathy of liver disease and liver transplantation. World J. Gas troenterol. 2006; 12 (48): 7725–7736. DOI: 10.3748/wjg.v12.i48.7725. PMID: 17203512
45. Журавель С.В., Андрейцева О.И., Донова Л.В., Джаграев К.Р., Чжао А.В. Профилактика и лечение сосудистых осложнений после трансплантации печени. Трансплантология. 2012; 1-2: 33-37.
46. Bakker C.M., Metselaar H.J., Groenland T.N., Terpstra O.T., Stibbe J. Increased fibrinolysis in orthotopic but not in heterotopic liver transplantation: the role of the anhepatic phase. Transpl. Int. 1992; 5 (Suppl 1): S173-S174. DOI: 10.1007/978-3-642-77423-2_54. PMID: 14621767
47. Bakker C.M., Metselaar H.J., Groenland T.N., Gomes M.J., Knot E.A., Hesselink E.J., Schalm S.W., Stibbe J., Terpstra O.T. Increased tissue-type plasminogen activator activity in orthotopic but not heterotopic liver transplantation: the role of the anhepatic period. Hepatology. 1992; 16 (2): 404-408. DOI: 10.1002/hep.1840160219. PMID: 1639350
48. Azad S.C., Kratzer M.A., Groh J., Welte M., Haller M., Pratschke E. Intraoperative monitoring and postoperative reevaluation of hemostasis in orthotopic liver transplantation. Semin. Thromb. Hemost. 1993; 19 (3): 233-237. DOI: 10.1055/s-2007-994031. PMID: 8362253
49. Paulsen A.W., Whitten C.W., Ramsay M.A., Klintmalm G.B. Considerations for anesthetic management during veno-venous bypassin adult hepatic transplantation. Anesth. Analg. 1989; 68 (4): 489-496. DOI: 10.1213/00000539-198904000-00012. PMID: 2648895
50. Scherer R., Giebler R., Erhard J., Lange R., Günnicker M., Schmutzler M., Paar D., Kox W.J. A new method of veno-venous bypass during human orthotopic liver transplantation. Anaesthesia. 1994; 49 (5): 398-402. DOI: 10.1111/j.1365-2044.1994.tb03471.x. PMID: 8209979
51. Shimauchi T., Yamaura K., Higashi M., Abe K., Yoshizumi T., Hoka S. Fibrinolysis in living donor liver transplantation recipients evaluated using thromboelastometry: impact on mortality. Transplant. Proc. 2017; 49 (9): 2117-2121. DOI: 10.1016/j.transproceed.2017.09.025. PMID: 29149971
52. Bakker C.M., Blankensteijn J.D., Schlejen P., Porte R.J., Gomes M.J., Lampe H.I., Stibbe J., Terpstra O.T. The effects of long-term graft preservation on intraoperative hemostatic changes in liver transplantation. A comparison between orthotopic and heterotopic transplantation in the pig. HPB Surg. 1994; 7 (4): 265-280. DOI: 10.1155/1994/27915. PMID: 8204546
53. Wolberg A.S., Meng Z.H., Monroe D.M.3rd, Hoffman M. A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function. J. Trauma. 2004; 56 (6): 1221–1228. DOI: 10.1097/01.TA.0000064328.97941.FC. PMID: 15211129
54. Martini W.Z. Coagulopathy by hypothermia and acidosis: mechanisms of thrombin generation and fibrinogen availability. J. Trauma 2009; 67 (1): 202–208. DOI: 10.1097/TA.0b013e3181a602a7. PMID: 19590336
55. Han S.B., Gwak M.S., Choi S.J., Kim M.H., Ko J.S., Kim G.S., Joo H.S. Effect of active airway warming on body core temperature during adult liver transplantation. Transplant. Proc. 2013; 45(1): 251-254. DOI: 10.1016/j.transproceed.2012.05.088. PMID: 23375310
56. Ghadimi K., Levy J.H., Welsby I.J. Perioperative management of the bleeding patient. Br. J. Anaesth. 2016; 117 (Suppl 3): iii18-iii30. DOI: 10.1093/bja/aew358. PMID: 27940453
57. Reynolds L., Beckmann J., Kurz A. Perioperative complications of hypothermia. Best Pract. Res. Clin. Anaesthesiol. 2008; 22 (4): 645-657. DOI: 10.1016/j.bpa.2008.07.005. PMID: 19137808
58. Pandey C.K., Singh A., Kajal K., Dhankhar M., Tandon M., Pandey V.K., Karna S.T. Intraoperative blood loss in orthotopic liver transplantation: the predictive factors. World J. Gastrointest. Surg. 2015; 7 (6): 86-93. DOI: 10.4240/wjgs.v7.i6.86. PMID: 26131330
59. Senzolo M., Cholongitas E., Thalheimer U., Riddell A., Agarwal S., Mallett S., Ferronato C., Burroughs A.K. Heparin-like effect in liver disease and liver transplantation. Clin. Liver Dis. 2009; 13 (1): 43-53. DOI: 10.1016/j.cld.2008.09.004. PMID: 19150308
60. Tomescu D., Popescu M., Jipa L., Fota R., Ungureanu D., Zamfir R., Orban C., Dima S.O., Popescu I. The impact of donor liver graft quality on postoperative outcome in liver transplant recipients. A single centre experience. Rom. J. Anaesth. Intensive Care. 2016; 23 (1): 19-26. DOI: 10.21454/rjaic.7518.231.gft. PMID: 28913473
61. Moriau M., Kestens P.J., Masure R. Heparin and antifibrinolytic agents during experimental hepatectomy and liver transplantation. Pathol. Eur. 1969; 4 (2): 172–182. PMID: 4896202
62. Porte R.J., Bontempo F.A., Knot E.A., Lewis J.H., Kang Y.G., Starzl T.E. Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation. Transplantation. 1989; 47 (6): 978-984. DOI: 10.1097/00007890198906000-00012. PMID: 2499962
63. Hutchison D.E., Genton E., Porter K.A., Daloze P.M., Huguet C., Brettschneider L., Groth C.G., Starzl T.E. Platelet changes following clinical and experimental hepatic homotransplantation. Arch. Surg. 1968; 97 (1): 27–33. DOI: 10.1001/archsurg.1968.01340010057003. PMID: 4232038
64. Reuvers C.B., Terpstra O.T., Groenland T.H., Boks A.L., Faithfull N.S., ten Kate F.W. Hemodynamics and coagulation in experimental auxiliary liver transplantation during fulminant hepatic failure. Ann. Surg. 1986; 204 (5): 552-558. DOI: 10.1097/00000658-198611000-00008. PMID: 3532973
65. Kang Y., Audu P. Coagulation and liver transplantation. Int. Anesthesiol. Clin. 2006; 44 (4): 17-36. DOI: 10.1097/01.aia.0000210811.77663.1e. PMID: 17033477
66. Шумаков В.И. (ред.). Трансплантология. М.: МИА; 2006: 310-330. ISBN: 5-89481-453-7
67. Schrem H., Klußmann A., Focken M., Emmanouilidis N., Oldhafer F., Klempnauer J., Kaltenborn A. Post-operative hemorrhage after liver transplantation: risk factors and long-term outcome. Ann. Transplant. 2016; 21: 46-55. DOI: 10.12659/AOT.895605. PMID: 26818716
68. Yuki K., Bu W., Shimaoka M., Eckenhoff R. Volatileanesthetics, not intravenous anesthetic propofol bind to and attenuate the activation of platelet receptor integrin αIIbβ3. PLoSOne. 2013; 8 (4): e60415. DOI: 10.1371/journal.pone.0060415. PMID: 23573252
69. Faraday N. Platelets, perioperative hemostasis, and anesthesia. Anesthesiology. 2002; 96 (5): 1042-1043. DOI: 10.1097/00000542-20020500000003. PMID: 11981140
70. Ueda I. The effects of volatile general anesthetics on adenosine diphosphateinduced platelet aggregation. Anesthesiology. 1971; 34 (5): 405408. DOI: 10.1097/00000542-197105000-00006. PMID: 5554584
71. Журавель С.В., Чугунов А.О., Салиенко А.А., Донова Л.В. Трансплантация печени, осложненная острым тромбозом воротной вены. Вестн. интенс. терапии. 2009; 3: 70-72.
72. Abuelkasem E., Lu S., Tanaka K., Planinsic R., Sakai T. Comparison between thrombelastography and thromboelastometry in hyperfibrinolysis detection during adult liver transplantation..Br. J. Anaesth. 2016; 116 (4): 507-512. DOI: 10.1093/bja/aew023. PMID: 26934942
73. Ozier Y., Pessione F., Samain E., Courtois F.; French Study Group on Blood Transfusion in Liver Transplantation. Institutional variability in transfusion practice for liver transplantation. Anesth. Analg. 2003; 97 (3): 671– 679. DOI: 10.1213/01.ANE.0000073354.38695.7C. PMID: 12933381
74. Hutten B.A., Lensing A.W., Kraaijenhagen R.A., Prins M.H. Safety of treatment with oral anticoagulants in the elderly. A systematic review. Drugs Aging. 1999; 14 (4): 303-312. DOI: 10.2165/00002512-19991404000005. PMID: 10319243
75. Anand S.S., Bates S., Ginsberg J.S., Levine M., Buller H., Prins M., Haley S., Kearon C., Hirsh J., Gent M. Reccurent venous thrombsis and heparin therapy: an evaluation of the importance of early activated partial tromboplastin times. Arch. Intern. Med. 1999; 159 (17): 2029-2032. DOI: 10.1001/archinte.159.17.2029. PMID: 10510988
76. Algarni A.A., Mourad M.M., Bramhall S.R. Anticoagulation and antiplatelets as prophylaxis for hepatic artery thrombosis after liver transplantation. World J. Hepatol. 2015; 7 (9): 1238-1243. DOI: 10.4254/wjh.v7.i9.1238. PMID: 26019738
77. Wall W.J., Grant D.R., Duff J.H., Kutt J.L., Ghent C.N. Blood transfusion requirements and renal function in patient undergoing liver transplantation without venous bypass. Transplant. Proc. 1987; 19 (4 Suppl 3): 1720. PMID: 3303529
78. de Boer M.T., Molenaar I.Q., Hendriks H.G., Slooff M.J., Porte R.J. Minimizing blood loss in liver transplantation: progress through research and evolution of techniques. Dig. Surg. 2005; 22 (4): 265-275. DOI: 10.1159/000088056. PMID: 16174983
79. de Boer M.T., Christensen M.C., Asmussen M., van der Hilst C.S., Hendriks H.G., Slooff M.J., Porte R.J. The impact of intraoperative transfusion of platelets and red blood cells on survival after liver transplantation. Anesth. Analg. 2008; 106 (1): 32–44. DOI: 10.1213/01.ane.0000289638. 26666.ed. PMID: 18165548
80. Cap A.P., Spinella P.C., Borgman M.A., Blackbourne L.H., Perkins J.G. Timing and location of blood product transfusion and outcomes in massively transfused combat casualties. J. Trauma Acute Care Surg. 2012; 73 (2 Suppl 1): S89–S94. DOI: 10.1097/TA.0b013e318260625a. PMID: 22847102
81. Phillips S.D., Maguire D., Deshpande R., Muiesan P., Bowles M.J., Rela M., Heaton N.D. A prospective study investigating the cost effectiveness of intraoperative blood salvage during liver transplantation. Transplantation. 2006; 81 (4): 536–540. DOI: 10.1097/01.tp.0000199318.17013.c5. PMID: 16495800
82. Massicotte L., Thibeault L., Beaulieu D., Roy J.D., Roy A. Evaluation of cell salvage autotransfusion utility during liver transplantation. HPB (Oxford). 2007; 9 (1): 52–57. DOI: 10.1080/13651820601090596. PMID: 18333113
83. Massicotte L., Thibeault L., Roy A. Classical notions of coagulation revisited in relation with blood losses, transfusion rate for 700 consecutive liver transplantations. Semin. Thromb. Hemost. 2015; 41 (5): 538-546. DOI: 10.1055/s-0035-1550428. PMID: 26080304
84. Kırnap M., Tezcaner T., Ayvazogl˘u Soy H.E., Akdur A., Yildirim S., Torgay A., Moray G., Haberal M. Efficacy of cell saver use in living-donor liver transplant. Exp. Clin. Transplant. 2015; 13 (Suppl 1): 315–317. DOI: 10.6002/ect.mesot2014.P153. PMID: 25894181
85. Liang T.B., Li D.L., Liang L., Li J.J., Bai X.L., Yu W., Wang W.L., Shen Y., Zhang M., Zheng S.S. Intraoperative blood salvage during liver transplan tation in patients with hepatocellular carcinoma: efficiency of leukocyte depletion filters in the removal of tumor cells. Transplantation. 2008; 85 (6): 863-869. DOI: 10.1097/TP.0b013e3181671f2e. PMID: 18360269
86. Araujo R.L., Pantanali C.A., Haddad L., Rocha Filho J.A., D’Albuquerque L.A., Andraus W. Does autologous blood transfusion during liver transplantation for hepatocellular carcinoma increase risk of recurrence? World J. Gastrointest. Surg. 2016; 8 (2): 161-168. DOI: 10.4240/wjgs.v8.i2.161. PMID: 26981190
87. Freire M.P., Soares Oshiro I.C., Bonazzi P.R., Guimarães T., Ramos Figueira E.R., Bacchella T., Costa S.F., Carneiro D’Albuquerque L.A., Abdala E. Surgical site infections in liver transplant recipients in the model for endstage liver disease era: an analysis of the epidemiology, risk factors, and outcomes. Liver Transpl. 2013; 19 (9): 1011–1019. DOI: 10.1002/lt.23682. PMID: 23744748
88. Reichert B., Kaltenborn A., Becker T., Schiffer M., Klempnauer J., Schrem H. Massive blood transfusion after the first cut in liver transplantation predicts renal outcome and survival. Langenbecks Arch. Surg. 2014; 399 (4): 429–440. DOI: 10.1007/s00423-014-1181-y. PMID: 24682384
89. Мороз В.В., Черныш А.М., Козлова Е.К., Сергунова В.А., Гудкова О.Е., Хорошилов С.Е., Онуфриевич А.Д., Костин А.И. Нарушения морфологии и наноструктуры мембран эритроцитов при длительном хранении эритроцитарной взвеси (исследование при помощи атомной силовой микроскопии). Бюл. эксперим. биологии и медицины. 2015; 159 (3): 390-394. DOI: 10.1007/s10517-015-2975-9. PMID: 26212816
90. Kozlova E., Chernysh A., Moroz V., Sergunova V., Gudkova O., Manchenko E. Morphology, membrane nanostructure and stiffness for quality assessment of packed red blood cells. Sci. Rep. 2017; 7 (1): 7846. DOI: 1038/s41598-017-08255-9. PMID: 28798476
91. Сергунова В.А., Гудкова О.Е., Манченко Е.А., Козлова Е.К., Бобринская И.Г., Черныш А.М., Козлов А.П. Влияние температуры эритроцитарной взвеси на морфологию и наноструктуру мембран клеток. Общая реаниматология. 2017; 13 (4): 30-37. DOI: 10.15360/1813-9779-20174-30-37
92. Wang S.C., Shieh J.F., Chang K.Y., Chu Y.C., Liu C.S., Loong C.C., Chan K.H., Mandell S., Tsou M.Y. Thromboelastography-guided transfusion decreases intraoperative blood transfusion during orthotopic liver transplantation: randomized clinical trial. Transplant. Proc. 2010; 42 (7): 2590–2593. DOI: 10.1016/j.transproceed.2010.05.144. PMID: 20832550
93. Hendriks H.G., Meijer K., de Wolf J.T., Klompmaker I.J., Porte R.J., de Kam P.J., Hagenaars A.J., Melsen T., Slooff M.J., van der Meer J. Reduced transfusion requirements by recombinant factor VIIa in orthotopic liver transplantation: a pilot study. Transplantation. 2001; 71 (3): 402-405. DOI: 10.1097/00007890-200102150-00011. PMID: 11233901
94. Pugliese F., Ruberto F., Summonti D., Perrella S., Cappannoli A., Tosi A., D’alio A., Bruno K., Martelli S., Celli P., Morabito V., Rossi M., Berloco P.B, Pietropaoli P. Activated recombinant factor VII in orthotopic liver transplantation. Transplant. Proc. 2007; 39 (6): 1883-1885. DOI: 10.1016/j.transproceed.2007.05.062. PMID: 17692642
95. Chavez-Tapia N.C., Alfaro-Lara R., Tellez-Avila F., Barrientos-Gutiérrez T., González-Chon O., Mendez-Sanchez N., Uribe M. Prophylactic activated recombinant factor VII in liver resection and liver transplantation: systematic review and meta-analysis. PLoS One. 2011; 6 (7): e22581. DOI: 10.1371/journal.pone.0022581. PMID: 21818342
96. Scheffert J.L., Taber D.J., Pilch N.A., McGillicuddy J.W., Baliga P.K., Chavin K.D. Timing of factor VIIa in liver transplantation impacts cost and clinical outcomes. Pharmacotherapy. 2013; 33 (5): 483-488. DOI: 10.1002/phar.1230. PMID: 23468226
97. Helfritz F.A., Stiefel P., Manns M.P., Klempnauer J., Lehner F., Lenzen H., Ciesek S. Use of recombinant factor VIIA as a risk factor for graft loss after orthotopic liver transplantation due to hepatic artery thrombosis. J. Bioequiv. Availab. 2016; 8: 8-12. DOI: 10.4172/jbb.1000259
98. Trzebicki J., Flakiewicz E., Kosieradzki M., Blaszczyk B., Kołacz M., Jureczko L., Pacholczyk M., Chmura A., Lagiewska B., Lisik W., Wasiak D., Kosson D., Kwiatkowski A., Lazowski T. The use of thromboelastometry in the assessment of hemostasis during orthotopic liver transplantation reduces the demand for blood products. Ann. Transplant. 2010; 15 (3): 19–24. PMID: 20877262
99. Molenaar I.Q., Warnaar N., Groen H., Tenvergert E.M., Slooff M.J., Porte R.J. Efficacy and safety of antifibrinolytic drugs in liver transplantation: a systematic review and meta-analysis. Am. J. Transplant. 2007; 7 (1): 185–194. DOI: 10.1111/j.1600-6143.2006.01591.x. PMID: 17227567
100. Kozek-Langenecker S.A., Afshari A., Albaladejo P., Santullano C.A., De Robertis E., Filipescu D.C., Fries D., Görlinger K., Haas T., Imberger G., Jacob M., Lancé M., Llau J., Mallett S., Meier J., Rahe-Meyer N., Samama C.M., Smith A., Solomon C., Van der Linden P., Wikkelsø A.J., Wouters P., Wyffels P. Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology. Eur. J. Anaesthesiol. 2013; 30 (6): 270–382. DOI: 10.1097/EJA.0b013e32835f4d5b. PMID: 23656742
101. Ogren M., Bergqvist D., Björck M., Acosta S., Eriksson H., Sternby N.H. Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies. World J. Gastroenterol. 2006; 12 (13): 2115-2119. DOI: 10.3748/wjg.v12.i13.2115. PMID: 16610067
102. Хорошилов С.Е., Никулин А.В. Детоксикация при критических состояниях: понимание научной проблемы в XXI веке (обзор). Общая реаниматология. 2017; 13 (5): 85-108. DOI: 10.15360/18139779-2017-5-85-108
103. Trzebicki J., Kosieradzki M., Flakiewicz E., Kuzminska G., Wasiak D., Pacholczyk M., Lagiewska B., Lisik W., Kosson D., Kulik A., Chmura A., Lazowski T. Detrimental effect of aprotinin ban on amount of blood loss during liver transplantation: single-center experience. Transplant. Proc. 2011; 43 (5): 1725–1727. DOI: 10.1016/j.transproceed.2011.01.182. PMID: 21693266
104. Schofield N., Sugavanam A., Thompson K., Mallett S.V. No increase in blood transfusions during liver transplantation since the withdrawal of aprotinin. Liver Transpl. 2014; 20 (5): 584–590. DOI: 10.1002/lt.23839. PMID: 24481770
105. Massicotte L., Lenis S., Thibeault L., Sassine M.P., Seal R.F., Roy A. Effect of low central venous pressure and phlebotomy on blood product transfusion requirements during liver transplantations. Liver Transpl. 2006; 12 (1): 117-123. DOI: 10.1002/lt.20559. PMID: 16382461
106. Massicotte L., Beaulieu D., Thibeault L., Roy J.D., Marleau D., Lapointe R., Roy A. Coagulation defects do not predict blood product requirements during liver transplantation. Transplantation 2008; 85 (7): 956962. DOI: 10.1097/TP.0b013e318168fcd4. PMID: 18408574
107. Schroeder R.A., Collins B.H., Tuttle-Newhall E., Robertson K., Plotkin J., Johnson L.B., Kuo P.C. Intraoperative fluid management during orthotopic liver transplantation. J. Cardiothorac. Vasc. Anesth. 2004; 18 (4): 438–441. DOI: 10.1053/j.jvca.2004.05.020. PMID: 15365923
108. Colomina M.J., Díez Lobo A., Garutti I., Gómez-Luque A., Llau J.V., Pita E. Perioperative use of prothrombin complex concentrates. Minerva Anestesiol. 2012; 78: 358-368. PMID: 22357373
109. Arshad F., Ickx B., van Beem R.T., Polak W., Grüne F., Nevens F., Ilmakunnas M., Koivusalo A.M., Isoniemi H., Strengers P.F., Groen H., Hendriks H.G., Lisman T., Pirenne J., Porte R.J. Prothrombin complex concentrate in the reduction of blood loss during orthotopicliver transplantation: PROTON-trial. BMC Surg. 2013; 13: 22. DOI: 0.1186/1471-2482-1322. PMID: 23815798
110. Quintero J., Ortega J., Miserachs M., Bueno J., Bilbao I., Charco R. Low plasma levels of antithrombin III in the early post-operative period following pediatric liver transplantation: should they be replaced? A singlecenter pilot study. Pediatr. Transplant. 2014; 18 (2): 185-189. DOI: 10.1111/petr.12217. PMID: 24438318
111. Allingstrup M., Wetterslev J., Ravn F.B., Møller A.M., Afshari A. Antithrombin III for critically ill patients. Cochrane Database Syst. Rev. 2016; 2: CD005370. DOI: 10.1002/14651858.CD005370.pub3. PMID: 26858174
Рецензия
Для цитирования:
Решетняк В.И., Журавель С.В., Кузнецова Н.К., Писарев В.М., Клычникова Е.В., Сюткин В.Е., Решетняк Т.М. Система гемостаза в норме и при трансплантации печени (обзор). Общая реаниматология. 2018;14(5):58-84. https://doi.org/10.15360/1813-9779-2018-5-58-84
For citation:
Reshetnyak V.I., Zhuravel S.V., Kuznetsova N.K., Pisarev V.М., Klychnikova E.V., Syutkin V.Е., Reshetnyak Т.M. The System of Blood Coagulation in Normal and in Liver Transplantation (Review). General Reanimatology. 2018;14(5):58-84. https://doi.org/10.15360/1813-9779-2018-5-58-84
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